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Title: A novel immune evasion strategy of Candida albicans: Proteolytic cleavage of a salivary antimicrobial peptideLanguage: InglésRepository: 34Subject: aspartic proteinase / histatin 5 / antiinfective agent / saliva protein / article / Candida albicans / cell activity / commensal / enzyme release / fungal cell / Human immunodeficiency virus infection / infection sensitivity / innate immunity / mouth mucosa / nonhuman / protein analysis / protein degradation / thrush / hydrolysis / immunology / metabolism / Anti-Infective Agents / Hydrolysis / Salivary Proteins and Peptides / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Genome-wide binding patterns of thyroid hormone receptor betaLanguage: InglésRepository: 34Subject: thyroid hormone receptor beta / transcription factor AP 1 / transcription factor CTCF / ligand / protein binding / RNA / 3' untranslated region / 5' untranslated region / animal experiment / animal tissue / article / binding kinetics / binding site / controlled study / gene cluster / gene control / gene expression / gene repression / gene sequence / gene targeting / genetic association / genetic transcription / genetic transfection / human / human cell / liver cell / mouse / nonhuman / nucleotide sequence / protein analysis / protein function / protein localization / sequence analysis / animal / C57BL mouse / cell line / chemistry / DNA microarray / DNA responsive element / DNA sequence / gene expression regulation / genome / HepG2 cell line / liver / metabolism / multigene family / plasmid / Animals / Binding Sites / Cell Line / Gene Expression Regulation / Genome / Hep G2 Cells / Humans / Ligands / Liver / Mice / Mice, Inbred C57BL / Multigene Family / Oligonucleotide Array Sequence Analysis / Plasmids / Protein Binding / Response Elements / Sequence Analysis, DNA / Thyroid Hormone Receptors beta / 7 INGENIERÍA Y TECNOLOGÍA
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Title: A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulenceLanguage: InglésRepository: 34Subject: amino acid / arginine / bacterial protein / histidine / protein Mga / transcriptome / unclassified drug / virulence factor / mry protein, Streptococcus pyogenes / amino acid substitution / animal experiment / animal model / Article / bacterial gene / bacterial genome / bacterial strain / bacterial virulence / bacterium culture / codon / controlled study / gene expression / gene sequence / human / human cell / infectious arthritis / Macaca fascicularis / mga gene / mouse / nonhuman / nuclear magnetic resonance imaging / phenotype / priority journal / regulator gene / single nucleotide polymorphism / skin infection / soft tissue infection / Streptococcus group A / animal / arthropathy / cell line / female / genetics / hairless mouse / metabolism / microbiology / missense mutation / pathogenicity / pathology / Streptococcus infection / Streptococcus pyogenes / Amino Acid Substitution / Animals / Bacterial Proteins / Cell Line / Female / Genome, Bacterial / Humans / Joint Diseases / Mice / Mice, Hairless / Mutation, Missense / Polymorphism, Single Nucleotide / Streptococcal Infections / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cellsLanguage: InglésRepository: 34Subject: barium / beta naphtoylbrevetoxin / brevenal / brevetoxin / calcium ion / ciguatoxin / ciguatoxin 1B / natural product / nicotine / SNARE protein / sodium ion / tetrodotoxin / unclassified drug / voltage gated sodium channel / antidote / calcium / catecholamine / drug derivative / sodium / sodium channel / thiobutabarbital / thiopental / animal cell / article / catecholamine release / chromaffin cell / ciguatera / controlled study / drug mechanism / exocytosis / neurosecretion / neurotoxicity / nonhuman / sodium cell level / sodium transport / animal / cattle / drug effect / metabolism / secretion / Bovinae / Ciguatera / Dinophyceae / Animals / Antidotes / Calcium / Catecholamines / Cattle / Chromaffin Cells / Ciguatera Poisoning / Ciguatoxins / Neurosecretion / Sodium / Sodium Channels / Thiopental / 7 INGENIERÍA Y TECNOLOGÍA
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Title: The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob miceLanguage: InglésRepository: 34Subject: eprotirome / hormone receptor stimulating agent / liothyronine / sobetirome / thyroid hormone receptor / thyroid hormone receptor agonist / triacylglycerol / unclassified drug / 3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid / acetic acid derivative / anilide / glucose 6 phosphatase / glucose blood level / phenol derivative / animal experiment / animal model / animal tissue / Article / body temperature / controlled study / glucose tolerance / glycemic control / insulin resistance / insulin sensitivity / liver level / male / mouse / nonalcoholic fatty liver / nonhuman / ob/ob mouse / agonists / animal / biosynthesis / dose response / drug effects / enzyme induction / metabolism / mouse mutant / Non-alcoholic Fatty Liver Disease / time factor / Mus / Acetates / Anilides / Animals / Blood Glucose / Body Temperature / Dose-Response Relationship, Drug / Enzyme Induction / Glucose-6-Phosphatase / Insulin Resistance / Male / Mice / Mice, Obese / Phenols / Receptors, Thyroid Hormone / Time Factors / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathwayLanguage: InglésRepository: 34Subject: mammalian target of rapamycin / nanoparticle / paclitaxel / phosphatidylinositol 3 kinase / protein kinase B / rapamycin / target of rapamycin kinase / animal experiment / animal model / animal tissue / antineoplastic activity / breast cancer / cancer inhibition / conference paper / controlled study / drug delivery system / drug potentiation / drug tumor level / female / in vitro study / liver / mouse / nanoencapsulation / nanopharmaceutics / nonhuman / particle size / protein phosphorylation / protein targeting / spleen / animal / apoptosis / cell proliferation / drug effects / human / Mammary Neoplasms, Animal / MCF 7 cell line / metabolism / nude mouse / signal transduction / tumor cell line / Animalia / Mus / Animals / Apoptosis / Cell Line, Tumor / Cell Proliferation / Female / Humans / MCF-7 Cells / Mice / Mice, Nude / Paclitaxel / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Signal Transduction / Sirolimus / TOR Serine-Threonine Kinases / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Changes in T-tubules and sarcoplasmic reticulum in ventricular myocytes in early cardiac hypertrophy in a pressure overload rat modelLanguage: InglésRepository: 34Subject: calcium ion / aniline derivative / calcium / Fluo 4 / fluorescent dye / ion / xanthene derivative / animal cell / animal experiment / animal model / animal tissue / aorta constriction / Article / beta adrenergic stimulation / bone mass / calcium signaling / cell count / cell structure / cell volume / controlled study / decay time constant / density / diffusion / ex vivo study / heart left ventricle overload / heart muscle cell / heart muscle contractility / heart performance / heart ventricle hypertrophy / heart weight / male / nonhuman / priority journal / rat / sarcolemma / sarcoplasmic reticulum / tissue distribution / transverse tubular system / animal / cardiac muscle cell / cardiomegaly / cell culture / chemistry / confocal microscopy / cytology / disease model / fluorescence recovery after photobleaching / metabolism / microtubule / pathology / pressure / Wistar rat / Aniline Compounds / Animals / Calcium / Calcium Signaling / Cardiomegaly / Cells, Cultured / Disease Models, Animal / Fluorescence Recovery After Photobleaching / Fluorescent Dyes / Ions / Male / Microscopy, Confocal / Microtubules / Myocytes, Cardiac / Pressure / Rats / Rats, Wistar / Sarcoplasmic Reticulum / Xanthenes / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Sensitive detection of norovirus using phage nanoparticle reporters in lateral-flow assayLanguage: InglésRepository: 34Subject: gold nanoparticle / nanoparticle / phage nanoparticle reporter / unclassified drug / antigen binding / Article / assay / controlled study / diagnostic test accuracy study / enzyme linked immunosorbent assay / intermethod comparison / lateral flow assay / limit of detection / nonhuman / Norwalk virus / sensitivity and specificity / virus detection / virus like agent / bacteriophage / bioassay / Caliciviridae Infections / Escherichia coli / gastroenteritis / genetics / human / isolation and purification / metabolism / Norovirus / procedures / United States / virology / Bacteria (microorganisms) / Bacteriophages / Biological Assay / Gastroenteritis / Humans / Nanoparticles / Sensitivity and Specificity / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Antibody derived peptides for detection of Ebola virus glycoproteinLanguage: InglésRepository: 34Subject: single chain fragment variable antibody / virus glycoprotein / glycoprotein / monoclonal antibody / peptide fragment / recombinant protein / virus antibody / virus envelope protein / Article / bacterium culture / controlled study / cost effectiveness analysis / Ebola hemorrhagic fever / Ebolavirus / enzyme linked immunosorbent assay / Escherichia coli / nonhuman / virus detection / Hemorrhagic Fever, Ebola / human / immunology / metabolism / virology / Antibodies, Monoclonal / Antibodies, Viral / Enzyme-Linked Immunosorbent Assay / Glycoproteins / Humans / Peptide Fragments / Recombinant Proteins / Viral Envelope Proteins / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown FatLanguage: InglésRepository: 34Subject: eprotirome / hormone receptor stimulating agent / propranolol / sobetirome / thyroid hormone receptor / thyroid hormone receptor agonist / unclassified drug / adipocyte / animal cell / animal experiment / animal tissue / Article / brown adipose tissue / cold tolerance / controlled study / in vitro study / male / metabolic disorder / mouse / nonhuman / obesity / pharmacological procedures / priority journal / receptor blocking / subcutaneous fat / thermogenesis / white adipose tissue / animal / brown adipocyte / C57BL mouse / energy metabolism / metabolism / physiology / white adipocyte / Adipocytes, Brown / Adipocytes, White / Adipose Tissue, Brown / Adipose Tissue, White / Animals / Energy Metabolism / Mice / Mice, Inbred C57BL / Obesity / Receptors, Thyroid Hormone / Thermogenesis / 7 INGENIERÍA Y TECNOLOGÍA
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