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Title: A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray databaseLanguage: InglésRepository: 34Subject: 1 naphthyl isothiocyanate / acetylsalicylic acid / allopurinol / allyl alcohol / amiodarone / azathioprine / benzbromarone / bromobenzene / carbamazepine / carbon tetrachloride / chlorpromazine / cimetidine / clofibrate / coumarin / cyclophosphamide / cytochrome P450 family 1 / diazepam / diclofenac / doxepin / ethionine / fluphenazine / flutamide / gemfibrozil / glibenclamide / griseofulvin / haloperidol / hexachlorobenzene / indometacin / paracetamol / unindexed drug / cytotoxin / algorithm / Article / cluster analysis / data base / gene expression / genomics / human / liver cell / liver toxicity / machine learning / microarray analysis / nonhuman / skin absorption / toxic hepatitis / xenobiotic metabolism / animal / DNA microarray / dose response / drug effects / genetic database / genetics / liver / metabolism / mouse / preclinical study / procedures / time factor / toxicogenetics / unsupervised machine learning / Animals / Chemical and Drug Induced Liver Injury / Cytotoxins / Databases, Genetic / Dose-Response Relationship, Drug / Drug Evaluation, Preclinical / Genomics / Humans / Liver / Mice / Oligonucleotide Array Sequence Analysis / Time Factors / Toxicogenetics / Unsupervised Machine Learning / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Fanconi Anemia and Laron SyndromeLanguage: InglésRepository: 34Subject: Fanconi anemia group A protein / Fanconi anemia group G protein / Fanconi anemia group I protein / Fanconi anemia group L protein / genomic DNA / growth hormone / IGFBP3 protein / PALB2 protein / protein / somatomedin binding protein 3 / somatomedin C / STAT5b protein / unclassified drug / growth hormone receptor / human growth hormone / IGF1 protein, human / IGFBP3 protein, human / adult / Article / biochemical analysis / case report / clinical feature / disease association / Fanconi anemia / female / genetic variation / heterozygote / hospital admission / human / Laron syndrome / missense mutation / molecular diagnosis / molecular pathology / next generation sequencing / physical examination / protein analysis / protein blood level / provocation test / short stature / signal transduction / tooth development / young adult / blood / body height / complication / genetics / metabolism / Mexico / pathology / Body Height / Fanconi Anemia / Female / Human Growth Hormone / Humans / Insulin-Like Growth Factor Binding Protein 3 / Insulin-Like Growth Factor I / Laron Syndrome / Receptors, Somatotropin / Signal Transduction / Young Adult / 7 INGENIERÍA Y TECNOLOGÍA
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