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Title: Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteinsLanguage: InglésRepository: 34Subject: angiotensin II / calcium / connective tissue growth factor / contractile protein / protein Grem1 / scleroprotein / somatomedin B / somatomedin B receptor / somatomedin binding protein 1 / somatomedin binding protein 2 / somatomedin binding protein 3 / somatomedin binding protein 4 / somatomedin binding protein 5 / somatomedin binding protein 6 / somatomedin C / somatomedin C receptor / unclassified drug / bradykinin / animal experiment / animal model / animal tissue / Article / calcium homeostasis / controlled study / coronary artery blood flow / Ctgf gene / extracellular matrix / gene / gene expression / Grem1 gene / heart muscle contractility / heart muscle fibrosis / heart weight / histology / Igf1 gene / Igf1r gene / Igf2 gene / Igf2r gene / Igfbp1 gene / Igfbp2 gene / Igfbp3 gene / Igfbp4 gene / Igfbp5 gene / Igfbp6 gene / male / mouse / nonhuman / protein blood level / real time polymerase chain reaction / regulatory mechanism / reperfusion injury / animal / body weight / cardiac muscle / deficiency / drug effects / gene expression regulation / genetics / heart contraction / hemodynamics / metabolism / organ size / pathology / perfusion / transgenic mouse / vasoconstriction / vasodilatation / Angiotensin II / Animals / Body Weight / Bradykinin / Extracellular Matrix / Gene Expression Regulation / Hemodynamics / Insulin-Like Growth Factor I / Mice, Transgenic / Myocardial Contraction / Myocardium / Organ Size / Perfusion / Real-Time Polymerase Chain Reaction / Vasoconstriction / Vasodilation / 7 INGENIERÍA Y TECNOLOGÍA
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