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7 INGENIERÍA Y TECNOLOGÍA
(19)
Animals
(19)
animal
(19)
nonhuman
(19)
controlled study
(16)
animal experiment
(15)
Article
(14)
metabolism
(14)
mouse
(11)
unclassified drug
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2017
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Inglés
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Subject:
animal experiment
Subject:
animal tissue
Subject:
nonhuman
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Title:
From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”
Language:
Inglés
Repository:
34
Subject:
high density lipoprotein cholesterol
/
high mobility group B1 protein
/
macrophage migration inhibition factor
/
macrophage migration inhibition factor 2
/
pancreatic ribonuclease
/
protein kinase B
/
reactive oxygen metabolite
/
STAT3 protein
/
toll like receptor 4
/
troponin I
/
troponin T
/
tumor necrosis factor
/
unclassified drug
/
vascular endothelial cadherin
/
atherectomy
/
atherogenesis
/
atherosclerosis
/
cardiac muscle cell
/
cardiovascular magnetic resonance
/
chronic kidney disease
/
cohort analysis
/
comorbidity
/
coronary artery bypass graft
/
disease association
/
disease course
/
disseminated intravascular clotting
/
drug eluting stent
/
Escherichia coli
/
heart infarction size
/
heart mitochondrion
/
heart protection
/
heart surgery
/
hemolytic uremic syndrome
/
human
/
immunosuppressive treatment
/
immunothrombosis
/
in vivo study
/
innate immunity
/
insulin dependent diabetes mellitus
/
multicenter study (topic)
/
myocardial ischemia reperfusion injury
/
non ST segment elevation myocardial infarction
/
nonhuman
/
oxidative stress
/
percutaneous coronary intervention
/
pilot study
/
protein expression
/
protein phosphorylation
/
randomized controlled trial (topic)
/
retinopathy
/
Review
/
sepsis
/
signal transduction
/
ST segment elevation myocardial infarction
/
thrombosis
/
animal
/
cardiology
/
cardiovascular disease
/
procedures
/
theranostic nanomedicine
/
trends
/
Animals
/
Cardiology
/
Cardiovascular Diseases
/
Humans
/
Theranostic Nanomedicine
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Cell source determines the immunological impact of biomimetic nanoparticles
Language:
Inglés
Repository:
34
Subject:
Antigen-antibody reactions
/
Biocompatibility
/
Biomimetics
/
Cell membranes
/
Drug delivery
/
Drug products
/
Immunology
/
Nanoparticles
/
Biomimetic nanoparticles
/
Biomimicry
/
Comprehensive evaluation
/
Immunobiology
/
Immunological effects
/
Nanovector
/
Systemic administration
/
Time-lapse microscopy
/
Biological materials
/
alanine aminotransferase
/
aspartate aminotransferase
/
biomimetic material
/
creatinine
/
gamma interferon
/
interleukin 10
/
interleukin 12
/
interleukin 1alpha
/
interleukin 1beta
/
interleukin 2
/
interleukin 3
/
interleukin 6
/
leukolike vector
/
multistage nanovector
/
nanocarrier
/
nanoparticle
/
reactive oxygen metabolite
/
transcription factor RelA
/
tumor necrosis factor alpha
/
unclassified drug
/
biomaterial
/
nanocapsule
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
biocompatibility
/
cell interaction
/
controlled study
/
cytokine release
/
drug delivery system
/
human
/
human cell
/
in vitro study
/
in vivo study
/
internalization
/
leukocyte membrane
/
liver function
/
macrophage
/
mononuclear phagocyte
/
mouse
/
nonhuman
/
opsonization
/
phagocytosis
/
priority journal
/
protein expression
/
static electricity
/
surface charge
/
time lapse imaging
/
zeta potential
/
animal
/
Bagg albino mouse
/
cell culture
/
comparative study
/
drug effects
/
evaluation study
/
immunology
/
innate immunity
/
leukocyte
/
Animals
/
Biocompatible Materials
/
Biomimetic Materials
/
Cells, Cultured
/
Immunity, Innate
/
Leukocytes
/
Mice
/
Mice, Inbred BALB C
/
Nanocapsules
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Genome-wide binding patterns of thyroid hormone receptor beta
Language:
Inglés
Repository:
34
Subject:
thyroid hormone receptor beta
/
transcription factor AP 1
/
transcription factor CTCF
/
ligand
/
protein binding
/
RNA
/
3' untranslated region
/
5' untranslated region
/
animal experiment
/
animal tissue
/
article
/
binding kinetics
/
binding site
/
controlled study
/
gene cluster
/
gene control
/
gene expression
/
gene repression
/
gene sequence
/
gene targeting
/
genetic association
/
genetic transcription
/
genetic transfection
/
human
/
human cell
/
liver cell
/
mouse
/
nonhuman
/
nucleotide sequence
/
protein analysis
/
protein function
/
protein localization
/
sequence analysis
/
animal
/
C57BL mouse
/
cell line
/
chemistry
/
DNA microarray
/
DNA responsive element
/
DNA sequence
/
gene expression regulation
/
genome
/
HepG2 cell line
/
liver
/
metabolism
/
multigene family
/
plasmid
/
Animals
/
Binding Sites
/
Cell Line
/
Gene Expression Regulation
/
Genome
/
Hep G2 Cells
/
Humans
/
Ligands
/
Liver
/
Mice
/
Mice, Inbred C57BL
/
Multigene Family
/
Oligonucleotide Array Sequence Analysis
/
Plasmids
/
Protein Binding
/
Response Elements
/
Sequence Analysis, DNA
/
Thyroid Hormone Receptors beta
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulence
Language:
Inglés
Repository:
34
Subject:
amino acid
/
arginine
/
bacterial protein
/
histidine
/
protein Mga
/
transcriptome
/
unclassified drug
/
virulence factor
/
mry protein, Streptococcus pyogenes
/
amino acid substitution
/
animal experiment
/
animal model
/
Article
/
bacterial gene
/
bacterial genome
/
bacterial strain
/
bacterial virulence
/
bacterium culture
/
codon
/
controlled study
/
gene expression
/
gene sequence
/
human
/
human cell
/
infectious arthritis
/
Macaca fascicularis
/
mga gene
/
mouse
/
nonhuman
/
nuclear magnetic resonance imaging
/
phenotype
/
priority journal
/
regulator gene
/
single nucleotide polymorphism
/
skin infection
/
soft tissue infection
/
Streptococcus group A
/
animal
/
arthropathy
/
cell line
/
female
/
genetics
/
hairless mouse
/
metabolism
/
microbiology
/
missense mutation
/
pathogenicity
/
pathology
/
Streptococcus infection
/
Streptococcus pyogenes
/
Amino Acid Substitution
/
Animals
/
Bacterial Proteins
/
Cell Line
/
Female
/
Genome, Bacterial
/
Humans
/
Joint Diseases
/
Mice
/
Mice, Hairless
/
Mutation, Missense
/
Polymorphism, Single Nucleotide
/
Streptococcal Infections
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Brevenal inhibits pacific ciguatoxin-1B-induced neurosecretion from bovine chromaffin cells
Language:
Inglés
Repository:
34
Subject:
barium
/
beta naphtoylbrevetoxin
/
brevenal
/
brevetoxin
/
calcium ion
/
ciguatoxin
/
ciguatoxin 1B
/
natural product
/
nicotine
/
SNARE protein
/
sodium ion
/
tetrodotoxin
/
unclassified drug
/
voltage gated sodium channel
/
antidote
/
calcium
/
catecholamine
/
drug derivative
/
sodium
/
sodium channel
/
thiobutabarbital
/
thiopental
/
animal cell
/
article
/
catecholamine release
/
chromaffin cell
/
ciguatera
/
controlled study
/
drug mechanism
/
exocytosis
/
neurosecretion
/
neurotoxicity
/
nonhuman
/
sodium cell level
/
sodium transport
/
animal
/
cattle
/
drug effect
/
metabolism
/
secretion
/
Bovinae
/
Ciguatera
/
Dinophyceae
/
Animals
/
Antidotes
/
Calcium
/
Catecholamines
/
Cattle
/
Chromaffin Cells
/
Ciguatera Poisoning
/
Ciguatoxins
/
Neurosecretion
/
Sodium
/
Sodium Channels
/
Thiopental
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
liothyronine
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
triacylglycerol
/
unclassified drug
/
3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
/
acetic acid derivative
/
anilide
/
glucose 6 phosphatase
/
glucose blood level
/
phenol derivative
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
body temperature
/
controlled study
/
glucose tolerance
/
glycemic control
/
insulin resistance
/
insulin sensitivity
/
liver level
/
male
/
mouse
/
nonalcoholic fatty liver
/
nonhuman
/
ob/ob mouse
/
agonists
/
animal
/
biosynthesis
/
dose response
/
drug effects
/
enzyme induction
/
metabolism
/
mouse mutant
/
Non-alcoholic Fatty Liver Disease
/
time factor
/
Mus
/
Acetates
/
Anilides
/
Animals
/
Blood Glucose
/
Body Temperature
/
Dose-Response Relationship, Drug
/
Enzyme Induction
/
Glucose-6-Phosphatase
/
Insulin Resistance
/
Male
/
Mice
/
Mice, Obese
/
Phenols
/
Receptors, Thyroid Hormone
/
Time Factors
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway
Language:
Inglés
Repository:
34
Subject:
mammalian target of rapamycin
/
nanoparticle
/
paclitaxel
/
phosphatidylinositol 3 kinase
/
protein kinase B
/
rapamycin
/
target of rapamycin kinase
/
animal experiment
/
animal model
/
animal tissue
/
antineoplastic activity
/
breast cancer
/
cancer inhibition
/
conference paper
/
controlled study
/
drug delivery system
/
drug potentiation
/
drug tumor level
/
female
/
in vitro study
/
liver
/
mouse
/
nanoencapsulation
/
nanopharmaceutics
/
nonhuman
/
particle size
/
protein phosphorylation
/
protein targeting
/
spleen
/
animal
/
apoptosis
/
cell proliferation
/
drug effects
/
human
/
Mammary Neoplasms, Animal
/
MCF 7 cell line
/
metabolism
/
nude mouse
/
signal transduction
/
tumor cell line
/
Animalia
/
Mus
/
Animals
/
Apoptosis
/
Cell Line, Tumor
/
Cell Proliferation
/
Female
/
Humans
/
MCF-7 Cells
/
Mice
/
Mice, Nude
/
Paclitaxel
/
Phosphatidylinositol 3-Kinases
/
Proto-Oncogene Proteins c-akt
/
Signal Transduction
/
Sirolimus
/
TOR Serine-Threonine Kinases
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Changes in T-tubules and sarcoplasmic reticulum in ventricular myocytes in early cardiac hypertrophy in a pressure overload rat model
Language:
Inglés
Repository:
34
Subject:
calcium ion
/
aniline derivative
/
calcium
/
Fluo 4
/
fluorescent dye
/
ion
/
xanthene derivative
/
animal cell
/
animal experiment
/
animal model
/
animal tissue
/
aorta constriction
/
Article
/
beta adrenergic stimulation
/
bone mass
/
calcium signaling
/
cell count
/
cell structure
/
cell volume
/
controlled study
/
decay time constant
/
density
/
diffusion
/
ex vivo study
/
heart left ventricle overload
/
heart muscle cell
/
heart muscle contractility
/
heart performance
/
heart ventricle hypertrophy
/
heart weight
/
male
/
nonhuman
/
priority journal
/
rat
/
sarcolemma
/
sarcoplasmic reticulum
/
tissue distribution
/
transverse tubular system
/
animal
/
cardiac muscle cell
/
cardiomegaly
/
cell culture
/
chemistry
/
confocal microscopy
/
cytology
/
disease model
/
fluorescence recovery after photobleaching
/
metabolism
/
microtubule
/
pathology
/
pressure
/
Wistar rat
/
Aniline Compounds
/
Animals
/
Calcium
/
Calcium Signaling
/
Cardiomegaly
/
Cells, Cultured
/
Disease Models, Animal
/
Fluorescence Recovery After Photobleaching
/
Fluorescent Dyes
/
Ions
/
Male
/
Microscopy, Confocal
/
Microtubules
/
Myocytes, Cardiac
/
Pressure
/
Rats
/
Rats, Wistar
/
Sarcoplasmic Reticulum
/
Xanthenes
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
propranolol
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
unclassified drug
/
adipocyte
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
brown adipose tissue
/
cold tolerance
/
controlled study
/
in vitro study
/
male
/
metabolic disorder
/
mouse
/
nonhuman
/
obesity
/
pharmacological procedures
/
priority journal
/
receptor blocking
/
subcutaneous fat
/
thermogenesis
/
white adipose tissue
/
animal
/
brown adipocyte
/
C57BL mouse
/
energy metabolism
/
metabolism
/
physiology
/
white adipocyte
/
Adipocytes, Brown
/
Adipocytes, White
/
Adipose Tissue, Brown
/
Adipose Tissue, White
/
Animals
/
Energy Metabolism
/
Mice
/
Mice, Inbred C57BL
/
Obesity
/
Receptors, Thyroid Hormone
/
Thermogenesis
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Topical anti-inflammatory effects of isorhamnetin glycosides isolated from opuntia ficus-indica
Language:
Inglés
Repository:
34
Subject:
antiinflammatory agent
/
cyclooxygenase 2
/
flavonoid glycoside
/
indometacin
/
interleukin 6
/
isorhamnetin
/
isorhamnetin glucosyl pentoside
/
isorhamnetin glucosyl rhamnoside
/
isorhamnetin glucosyl rhamnosyl pentoside
/
isorhamnetin glucosyl rhamnosyl rhamnoside
/
isorhamnetin glycoside derivative
/
nitric oxide
/
Opuntia ficus indica extract
/
plant extract
/
tumor necrosis factor alpha
/
unclassified drug
/
3-methylquercetin
/
cytokine
/
glycoside
/
quercetin
/
animal cell
/
animal experiment
/
animal model
/
antiinflammatory activity
/
Article
/
cell proliferation
/
cell viability
/
controlled study
/
cytokine production
/
drug identification
/
ear edema
/
enzyme activity
/
in vitro study
/
in vivo study
/
macrophage
/
male
/
medicinal plant
/
mouse
/
nonhuman
/
Opuntia ficus-indica
/
rat
/
analogs and derivatives
/
animal
/
chemistry
/
dose response
/
immunology
/
Opuntia
/
Otitis Externa
/
treatment outcome
/
Wistar rat
/
Animals
/
Anti-Inflammatory Agents
/
Cytokines
/
Dose-Response Relationship, Drug
/
Glycosides
/
Male
/
Plant Extracts
/
Quercetin
/
Rats
/
Rats, Wistar
/
Treatment Outcome
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
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