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Title: Genome-wide binding patterns of thyroid hormone receptor betaLanguage: InglésRepository: 34Subject: thyroid hormone receptor beta / transcription factor AP 1 / transcription factor CTCF / ligand / protein binding / RNA / 3' untranslated region / 5' untranslated region / animal experiment / animal tissue / article / binding kinetics / binding site / controlled study / gene cluster / gene control / gene expression / gene repression / gene sequence / gene targeting / genetic association / genetic transcription / genetic transfection / human / human cell / liver cell / mouse / nonhuman / nucleotide sequence / protein analysis / protein function / protein localization / sequence analysis / animal / C57BL mouse / cell line / chemistry / DNA microarray / DNA responsive element / DNA sequence / gene expression regulation / genome / HepG2 cell line / liver / metabolism / multigene family / plasmid / Animals / Binding Sites / Cell Line / Gene Expression Regulation / Genome / Hep G2 Cells / Humans / Ligands / Liver / Mice / Mice, Inbred C57BL / Multigene Family / Oligonucleotide Array Sequence Analysis / Plasmids / Protein Binding / Response Elements / Sequence Analysis, DNA / Thyroid Hormone Receptors beta / 7 INGENIERÍA Y TECNOLOGÍA
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Title: A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulenceLanguage: InglésRepository: 34Subject: amino acid / arginine / bacterial protein / histidine / protein Mga / transcriptome / unclassified drug / virulence factor / mry protein, Streptococcus pyogenes / amino acid substitution / animal experiment / animal model / Article / bacterial gene / bacterial genome / bacterial strain / bacterial virulence / bacterium culture / codon / controlled study / gene expression / gene sequence / human / human cell / infectious arthritis / Macaca fascicularis / mga gene / mouse / nonhuman / nuclear magnetic resonance imaging / phenotype / priority journal / regulator gene / single nucleotide polymorphism / skin infection / soft tissue infection / Streptococcus group A / animal / arthropathy / cell line / female / genetics / hairless mouse / metabolism / microbiology / missense mutation / pathogenicity / pathology / Streptococcus infection / Streptococcus pyogenes / Amino Acid Substitution / Animals / Bacterial Proteins / Cell Line / Female / Genome, Bacterial / Humans / Joint Diseases / Mice / Mice, Hairless / Mutation, Missense / Polymorphism, Single Nucleotide / Streptococcal Infections / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathwayLanguage: InglésRepository: 34Subject: mammalian target of rapamycin / nanoparticle / paclitaxel / phosphatidylinositol 3 kinase / protein kinase B / rapamycin / target of rapamycin kinase / animal experiment / animal model / animal tissue / antineoplastic activity / breast cancer / cancer inhibition / conference paper / controlled study / drug delivery system / drug potentiation / drug tumor level / female / in vitro study / liver / mouse / nanoencapsulation / nanopharmaceutics / nonhuman / particle size / protein phosphorylation / protein targeting / spleen / animal / apoptosis / cell proliferation / drug effects / human / Mammary Neoplasms, Animal / MCF 7 cell line / metabolism / nude mouse / signal transduction / tumor cell line / Animalia / Mus / Animals / Apoptosis / Cell Line, Tumor / Cell Proliferation / Female / Humans / MCF-7 Cells / Mice / Mice, Nude / Paclitaxel / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Signal Transduction / Sirolimus / TOR Serine-Threonine Kinases / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Detection of autoantibodies to vascular endothelial growth factor Receptor-3 in bile duct ligated rats and correlations with a panel of traditional markers of liver diseasesLanguage: InglésRepository: 34Subject: aminotransferase / autoantibody / bilirubin / vasculotropin receptor 3 / Fgfr3 protein, mouse / fibroblast growth factor receptor 3 / tumor antigen / animal experiment / animal tissue / antibody blood level / antibody detection / Article / bile duct ligation / bilirubin blood level / cholestasis / controlled study / disease marker / enzyme linked immunosorbent assay / liver disease / liver fibrosis / liver injury / male / nonhuman / priority journal / rat / animal / disease model / human / immunology / metabolism / Wistar rat / Animals / Antigens, Neoplasm / Autoantibodies / Bilirubin / Cholestasis / Disease Models, Animal / Humans / Liver Diseases / Male / Rats / Rats, Wistar / Receptor, Fibroblast Growth Factor, Type 3 / 7 INGENIERÍA Y TECNOLOGÍA
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Title: An Influenza A/H1N1/2009 hemagglutinin vaccine produced in Escherichia coliLanguage: InglésRepository: 34Subject: hemagglutinin 63-286 / influenza vaccine / Influenza virus hemagglutinin / neutralizing antibody / recombinant protein / unclassified drug / virus antibody / virus hemagglutinin / animal cell / animal experiment / animal model / antibody production / antigen binding / article / bioassay / cell lysate / controlled study / dose response / drug binding / drug dose comparison / drug purification / Escherichia coli / ferret / human / immunogenicity / influenza A (H1N1) / Influenza virus A H1N1 / molecular recognition / nonhuman / nucleotide sequence / protein expression / protein folding / protein purification / single drug dose / ultracentrifugation / vaccine production / animal / blood / chemistry / enzyme linked immunosorbent assay / genetics / immunology / metabolism / reverse transcription polymerase chain reaction / Adolescent / Adult / Aged / Aged, 80 and over / Antibodies, Viral / Australia / Child / Child, Preschool / Cohort Studies / Humans / Influenza A Virus, H1N1 Subtype / Influenza, Human / Male / Middle Aged / Pandemics / Seasons / Young Adult / Animals / Enzyme-Linked Immunosorbent Assay / Ferrets / Hemagglutinins, Viral / Influenza Vaccines / Protein Folding / Reverse Transcriptase Polymerase Chain Reaction / Bacteria (microorganisms) / Hexapoda / Mammalia / Mustela / Prokaryota / 7 INGENIERÍA Y TECNOLOGÍA
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Title: A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray databaseLanguage: InglésRepository: 34Subject: 1 naphthyl isothiocyanate / acetylsalicylic acid / allopurinol / allyl alcohol / amiodarone / azathioprine / benzbromarone / bromobenzene / carbamazepine / carbon tetrachloride / chlorpromazine / cimetidine / clofibrate / coumarin / cyclophosphamide / cytochrome P450 family 1 / diazepam / diclofenac / doxepin / ethionine / fluphenazine / flutamide / gemfibrozil / glibenclamide / griseofulvin / haloperidol / hexachlorobenzene / indometacin / paracetamol / unindexed drug / cytotoxin / algorithm / Article / cluster analysis / data base / gene expression / genomics / human / liver cell / liver toxicity / machine learning / microarray analysis / nonhuman / skin absorption / toxic hepatitis / xenobiotic metabolism / animal / DNA microarray / dose response / drug effects / genetic database / genetics / liver / metabolism / mouse / preclinical study / procedures / time factor / toxicogenetics / unsupervised machine learning / Animals / Chemical and Drug Induced Liver Injury / Cytotoxins / Databases, Genetic / Dose-Response Relationship, Drug / Drug Evaluation, Preclinical / Genomics / Humans / Liver / Mice / Oligonucleotide Array Sequence Analysis / Time Factors / Toxicogenetics / Unsupervised Machine Learning / 7 INGENIERÍA Y TECNOLOGÍA
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