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34
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7 INGENIERÍA Y TECNOLOGÍA
(3)
Animals
(3)
Article
(3)
animal
(3)
genetics
(3)
metabolism
(3)
mouse
(3)
nonhuman
(3)
Gene Expression Regulation
(2)
Insulin-Like Growth Factor I
(2)
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2017
(3)
2018
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Artículo
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Inglés
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Subject:
Nutrición animal
Subject:
mouse
Year:
2017
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3
results
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Title:
A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database
Language:
Inglés
Repository:
34
Subject:
1 naphthyl isothiocyanate
/
acetylsalicylic acid
/
allopurinol
/
allyl alcohol
/
amiodarone
/
azathioprine
/
benzbromarone
/
bromobenzene
/
carbamazepine
/
carbon tetrachloride
/
chlorpromazine
/
cimetidine
/
clofibrate
/
coumarin
/
cyclophosphamide
/
cytochrome P450 family 1
/
diazepam
/
diclofenac
/
doxepin
/
ethionine
/
fluphenazine
/
flutamide
/
gemfibrozil
/
glibenclamide
/
griseofulvin
/
haloperidol
/
hexachlorobenzene
/
indometacin
/
paracetamol
/
unindexed drug
/
cytotoxin
/
algorithm
/
Article
/
cluster analysis
/
data base
/
gene expression
/
genomics
/
human
/
liver cell
/
liver toxicity
/
machine learning
/
microarray analysis
/
nonhuman
/
skin absorption
/
toxic hepatitis
/
xenobiotic metabolism
/
animal
/
DNA microarray
/
dose response
/
drug effects
/
genetic database
/
genetics
/
liver
/
metabolism
/
mouse
/
preclinical study
/
procedures
/
time factor
/
toxicogenetics
/
unsupervised machine learning
/
Animals
/
Chemical and Drug Induced Liver Injury
/
Cytotoxins
/
Databases, Genetic
/
Dose-Response Relationship, Drug
/
Drug Evaluation, Preclinical
/
Genomics
/
Humans
/
Liver
/
Mice
/
Oligonucleotide Array Sequence Analysis
/
Time Factors
/
Toxicogenetics
/
Unsupervised Machine Learning
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture
Language:
Inglés
Repository:
34
Subject:
acute phase protein
/
autacoid
/
lipid
/
messenger RNA
/
scleroprotein
/
somatomedin C
/
cadherin
/
cytoskeleton protein
/
insulin-like growth factor-1, mouse
/
somatomedin receptor
/
tight junction protein
/
acute phase response
/
animal experiment
/
animal tissue
/
Article
/
cell junction
/
cell polarity
/
controlled study
/
cytoskeleton
/
extracellular matrix
/
gene expression regulation
/
gene overexpression
/
heterozygosity
/
histology
/
igf1 gene
/
inflammation
/
lipid peroxidation
/
liver structure
/
liver tissue
/
male
/
microarray analysis
/
mouse
/
murine model
/
nonhuman
/
oxidative stress
/
protein analysis
/
protein blood level
/
protein deficiency
/
protein function
/
reverse transcription polymerase chain reaction
/
wild type
/
animal
/
comparative study
/
cross breeding
/
desmosome
/
gene expression profiling
/
genetics
/
hepatitis
/
immunology
/
liver
/
metabolism
/
pathology
/
subcutaneous drug administration
/
transgenic mouse
/
Acute-Phase Proteins
/
Animals
/
Cadherins
/
Crosses, Genetic
/
Cytoskeletal Proteins
/
Desmosomes
/
Extracellular Matrix Proteins
/
Gene Expression Profiling
/
Gene Expression Regulation
/
Hepatitis
/
Inflammation Mediators
/
Injections, Subcutaneous
/
Insulin-Like Growth Factor I
/
Lipid Peroxidation
/
Liver
/
Male
/
Mice
/
Mice, Transgenic
/
Oxidative Stress
/
Receptors, Somatomedin
/
Tight Junction Proteins
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins
Language:
Inglés
Repository:
34
Subject:
angiotensin II
/
calcium
/
connective tissue growth factor
/
contractile protein
/
protein Grem1
/
scleroprotein
/
somatomedin B
/
somatomedin B receptor
/
somatomedin binding protein 1
/
somatomedin binding protein 2
/
somatomedin binding protein 3
/
somatomedin binding protein 4
/
somatomedin binding protein 5
/
somatomedin binding protein 6
/
somatomedin C
/
somatomedin C receptor
/
unclassified drug
/
bradykinin
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
calcium homeostasis
/
controlled study
/
coronary artery blood flow
/
Ctgf gene
/
extracellular matrix
/
gene
/
gene expression
/
Grem1 gene
/
heart muscle contractility
/
heart muscle fibrosis
/
heart weight
/
histology
/
Igf1 gene
/
Igf1r gene
/
Igf2 gene
/
Igf2r gene
/
Igfbp1 gene
/
Igfbp2 gene
/
Igfbp3 gene
/
Igfbp4 gene
/
Igfbp5 gene
/
Igfbp6 gene
/
male
/
mouse
/
nonhuman
/
protein blood level
/
real time polymerase chain reaction
/
regulatory mechanism
/
reperfusion injury
/
animal
/
body weight
/
cardiac muscle
/
deficiency
/
drug effects
/
gene expression regulation
/
genetics
/
heart contraction
/
hemodynamics
/
metabolism
/
organ size
/
pathology
/
perfusion
/
transgenic mouse
/
vasoconstriction
/
vasodilatation
/
Angiotensin II
/
Animals
/
Body Weight
/
Bradykinin
/
Extracellular Matrix
/
Gene Expression Regulation
/
Hemodynamics
/
Insulin-Like Growth Factor I
/
Mice, Transgenic
/
Myocardial Contraction
/
Myocardium
/
Organ Size
/
Perfusion
/
Real-Time Polymerase Chain Reaction
/
Vasoconstriction
/
Vasodilation
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
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