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7 INGENIERÍA Y TECNOLOGÍA
(15)
Animals
(15)
Article
(15)
animal
(15)
nonhuman
(14)
animal experiment
(12)
controlled study
(12)
metabolism
(10)
mouse
(9)
animal tissue
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Subject:
Companion animal
Subject:
animal model
Subject:
Article
Language:
Inglés
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Year
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Title:
A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulence
Language:
Inglés
Repository:
34
Subject:
amino acid
/
arginine
/
bacterial protein
/
histidine
/
protein Mga
/
transcriptome
/
unclassified drug
/
virulence factor
/
mry protein, Streptococcus pyogenes
/
amino acid substitution
/
animal experiment
/
animal model
/
Article
/
bacterial gene
/
bacterial genome
/
bacterial strain
/
bacterial virulence
/
bacterium culture
/
codon
/
controlled study
/
gene expression
/
gene sequence
/
human
/
human cell
/
infectious arthritis
/
Macaca fascicularis
/
mga gene
/
mouse
/
nonhuman
/
nuclear magnetic resonance imaging
/
phenotype
/
priority journal
/
regulator gene
/
single nucleotide polymorphism
/
skin infection
/
soft tissue infection
/
Streptococcus group A
/
animal
/
arthropathy
/
cell line
/
female
/
genetics
/
hairless mouse
/
metabolism
/
microbiology
/
missense mutation
/
pathogenicity
/
pathology
/
Streptococcus infection
/
Streptococcus pyogenes
/
Amino Acid Substitution
/
Animals
/
Bacterial Proteins
/
Cell Line
/
Female
/
Genome, Bacterial
/
Humans
/
Joint Diseases
/
Mice
/
Mice, Hairless
/
Mutation, Missense
/
Polymorphism, Single Nucleotide
/
Streptococcal Infections
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
liothyronine
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
triacylglycerol
/
unclassified drug
/
3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
/
acetic acid derivative
/
anilide
/
glucose 6 phosphatase
/
glucose blood level
/
phenol derivative
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
body temperature
/
controlled study
/
glucose tolerance
/
glycemic control
/
insulin resistance
/
insulin sensitivity
/
liver level
/
male
/
mouse
/
nonalcoholic fatty liver
/
nonhuman
/
ob/ob mouse
/
agonists
/
animal
/
biosynthesis
/
dose response
/
drug effects
/
enzyme induction
/
metabolism
/
mouse mutant
/
Non-alcoholic Fatty Liver Disease
/
time factor
/
Mus
/
Acetates
/
Anilides
/
Animals
/
Blood Glucose
/
Body Temperature
/
Dose-Response Relationship, Drug
/
Enzyme Induction
/
Glucose-6-Phosphatase
/
Insulin Resistance
/
Male
/
Mice
/
Mice, Obese
/
Phenols
/
Receptors, Thyroid Hormone
/
Time Factors
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Changes in T-tubules and sarcoplasmic reticulum in ventricular myocytes in early cardiac hypertrophy in a pressure overload rat model
Language:
Inglés
Repository:
34
Subject:
calcium ion
/
aniline derivative
/
calcium
/
Fluo 4
/
fluorescent dye
/
ion
/
xanthene derivative
/
animal cell
/
animal experiment
/
animal model
/
animal tissue
/
aorta constriction
/
Article
/
beta adrenergic stimulation
/
bone mass
/
calcium signaling
/
cell count
/
cell structure
/
cell volume
/
controlled study
/
decay time constant
/
density
/
diffusion
/
ex vivo study
/
heart left ventricle overload
/
heart muscle cell
/
heart muscle contractility
/
heart performance
/
heart ventricle hypertrophy
/
heart weight
/
male
/
nonhuman
/
priority journal
/
rat
/
sarcolemma
/
sarcoplasmic reticulum
/
tissue distribution
/
transverse tubular system
/
animal
/
cardiac muscle cell
/
cardiomegaly
/
cell culture
/
chemistry
/
confocal microscopy
/
cytology
/
disease model
/
fluorescence recovery after photobleaching
/
metabolism
/
microtubule
/
pathology
/
pressure
/
Wistar rat
/
Aniline Compounds
/
Animals
/
Calcium
/
Calcium Signaling
/
Cardiomegaly
/
Cells, Cultured
/
Disease Models, Animal
/
Fluorescence Recovery After Photobleaching
/
Fluorescent Dyes
/
Ions
/
Male
/
Microscopy, Confocal
/
Microtubules
/
Myocytes, Cardiac
/
Pressure
/
Rats
/
Rats, Wistar
/
Sarcoplasmic Reticulum
/
Xanthenes
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Topical anti-inflammatory effects of isorhamnetin glycosides isolated from opuntia ficus-indica
Language:
Inglés
Repository:
34
Subject:
antiinflammatory agent
/
cyclooxygenase 2
/
flavonoid glycoside
/
indometacin
/
interleukin 6
/
isorhamnetin
/
isorhamnetin glucosyl pentoside
/
isorhamnetin glucosyl rhamnoside
/
isorhamnetin glucosyl rhamnosyl pentoside
/
isorhamnetin glucosyl rhamnosyl rhamnoside
/
isorhamnetin glycoside derivative
/
nitric oxide
/
Opuntia ficus indica extract
/
plant extract
/
tumor necrosis factor alpha
/
unclassified drug
/
3-methylquercetin
/
cytokine
/
glycoside
/
quercetin
/
animal cell
/
animal experiment
/
animal model
/
antiinflammatory activity
/
Article
/
cell proliferation
/
cell viability
/
controlled study
/
cytokine production
/
drug identification
/
ear edema
/
enzyme activity
/
in vitro study
/
in vivo study
/
macrophage
/
male
/
medicinal plant
/
mouse
/
nonhuman
/
Opuntia ficus-indica
/
rat
/
analogs and derivatives
/
animal
/
chemistry
/
dose response
/
immunology
/
Opuntia
/
Otitis Externa
/
treatment outcome
/
Wistar rat
/
Animals
/
Anti-Inflammatory Agents
/
Cytokines
/
Dose-Response Relationship, Drug
/
Glycosides
/
Male
/
Plant Extracts
/
Quercetin
/
Rats
/
Rats, Wistar
/
Treatment Outcome
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine
Language:
Inglés
Repository:
34
Subject:
ACTA2 protein
/
adenine
/
alpha smooth muscle actin
/
COL1A1 protein
/
collagen
/
connective tissue growth factor
/
creatinine
/
messenger RNA
/
transforming growth factor beta1
/
unclassified drug
/
urea
/
adipose derived stem cell
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
controlled study
/
creatinine blood level
/
creatinine urine level
/
human
/
human cell
/
kidney fibrosis
/
male
/
nonhuman
/
rat
/
stem cell transplantation
/
treatment outcome
/
urea blood level
/
adipose tissue
/
animal
/
cell culture
/
chemically induced
/
cytology
/
fibrosis
/
gene expression profiling
/
genetics
/
kidney disease
/
stem cell
/
Wistar rat
/
Adenine
/
Adipose Tissue
/
Animals
/
Cells, Cultured
/
Fibrosis
/
Gene Expression Profiling
/
Humans
/
Kidney Diseases
/
Male
/
Rats
/
Rats, Wistar
/
Stem Cells
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins
Language:
Inglés
Repository:
34
Subject:
angiotensin II
/
calcium
/
connective tissue growth factor
/
contractile protein
/
protein Grem1
/
scleroprotein
/
somatomedin B
/
somatomedin B receptor
/
somatomedin binding protein 1
/
somatomedin binding protein 2
/
somatomedin binding protein 3
/
somatomedin binding protein 4
/
somatomedin binding protein 5
/
somatomedin binding protein 6
/
somatomedin C
/
somatomedin C receptor
/
unclassified drug
/
bradykinin
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
calcium homeostasis
/
controlled study
/
coronary artery blood flow
/
Ctgf gene
/
extracellular matrix
/
gene
/
gene expression
/
Grem1 gene
/
heart muscle contractility
/
heart muscle fibrosis
/
heart weight
/
histology
/
Igf1 gene
/
Igf1r gene
/
Igf2 gene
/
Igf2r gene
/
Igfbp1 gene
/
Igfbp2 gene
/
Igfbp3 gene
/
Igfbp4 gene
/
Igfbp5 gene
/
Igfbp6 gene
/
male
/
mouse
/
nonhuman
/
protein blood level
/
real time polymerase chain reaction
/
regulatory mechanism
/
reperfusion injury
/
animal
/
body weight
/
cardiac muscle
/
deficiency
/
drug effects
/
gene expression regulation
/
genetics
/
heart contraction
/
hemodynamics
/
metabolism
/
organ size
/
pathology
/
perfusion
/
transgenic mouse
/
vasoconstriction
/
vasodilatation
/
Angiotensin II
/
Animals
/
Body Weight
/
Bradykinin
/
Extracellular Matrix
/
Gene Expression Regulation
/
Hemodynamics
/
Insulin-Like Growth Factor I
/
Mice, Transgenic
/
Myocardial Contraction
/
Myocardium
/
Organ Size
/
Perfusion
/
Real-Time Polymerase Chain Reaction
/
Vasoconstriction
/
Vasodilation
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Attacking the mosquito on multiple fronts: Insights from the Vector Control Optimization Model (VCOM) for malaria elimination
Language:
Inglés
Repository:
34
Subject:
larvicidal agent
/
Africa south of the Sahara
/
Anopheles arabiensis
/
Anopheles funestus
/
Anopheles gambiae
/
Article
/
bovine
/
disease transmission
/
feeding behavior
/
inoculation
/
insect bite
/
life cycle
/
malaria
/
model
/
mosquito control
/
population dynamics
/
prediction
/
simulation
/
vector control
/
zoology
/
animal
/
Anopheles
/
ecosystem
/
mosquito vector
/
physiology
/
procedures
/
sexual behavior
/
Animals
/
Ecosystem
/
Malaria
/
Mosquito Control
/
Mosquito Vectors
/
Sexual Behavior, Animal
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Cell source determines the immunological impact of biomimetic nanoparticles
Language:
Inglés
Repository:
34
Subject:
Antigen-antibody reactions
/
Biocompatibility
/
Biomimetics
/
Cell membranes
/
Drug delivery
/
Drug products
/
Immunology
/
Nanoparticles
/
Biomimetic nanoparticles
/
Biomimicry
/
Comprehensive evaluation
/
Immunobiology
/
Immunological effects
/
Nanovector
/
Systemic administration
/
Time-lapse microscopy
/
Biological materials
/
alanine aminotransferase
/
aspartate aminotransferase
/
biomimetic material
/
creatinine
/
gamma interferon
/
interleukin 10
/
interleukin 12
/
interleukin 1alpha
/
interleukin 1beta
/
interleukin 2
/
interleukin 3
/
interleukin 6
/
leukolike vector
/
multistage nanovector
/
nanocarrier
/
nanoparticle
/
reactive oxygen metabolite
/
transcription factor RelA
/
tumor necrosis factor alpha
/
unclassified drug
/
biomaterial
/
nanocapsule
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
biocompatibility
/
cell interaction
/
controlled study
/
cytokine release
/
drug delivery system
/
human
/
human cell
/
in vitro study
/
in vivo study
/
internalization
/
leukocyte membrane
/
liver function
/
macrophage
/
mononuclear phagocyte
/
mouse
/
nonhuman
/
opsonization
/
phagocytosis
/
priority journal
/
protein expression
/
static electricity
/
surface charge
/
time lapse imaging
/
zeta potential
/
animal
/
Bagg albino mouse
/
cell culture
/
comparative study
/
drug effects
/
evaluation study
/
immunology
/
innate immunity
/
leukocyte
/
Animals
/
Biocompatible Materials
/
Biomimetic Materials
/
Cells, Cultured
/
Immunity, Innate
/
Leukocytes
/
Mice
/
Mice, Inbred BALB C
/
Nanocapsules
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
propranolol
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
unclassified drug
/
adipocyte
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
brown adipose tissue
/
cold tolerance
/
controlled study
/
in vitro study
/
male
/
metabolic disorder
/
mouse
/
nonhuman
/
obesity
/
pharmacological procedures
/
priority journal
/
receptor blocking
/
subcutaneous fat
/
thermogenesis
/
white adipose tissue
/
animal
/
brown adipocyte
/
C57BL mouse
/
energy metabolism
/
metabolism
/
physiology
/
white adipocyte
/
Adipocytes, Brown
/
Adipocytes, White
/
Adipose Tissue, Brown
/
Adipose Tissue, White
/
Animals
/
Energy Metabolism
/
Mice
/
Mice, Inbred C57BL
/
Obesity
/
Receptors, Thyroid Hormone
/
Thermogenesis
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload
Language:
Inglés
Repository:
34
Subject:
Cell death
/
Microcontrollers
/
Calcium overload
/
Cell viability
/
Cellular injury
/
Intracellular Ca
/
Mitochondrial calcium uniporter
/
Mitochondrial dysfunction
/
Small interfering RNA
/
Therapeutic strategy
/
Calcium
/
calcium
/
small interfering RNA
/
calcium channel
/
cyclosporin
/
messenger RNA
/
mitochondrial calcium uniporter
/
reactive oxygen metabolite
/
animal cell
/
animal experiment
/
apoptosis
/
Article
/
cardiac muscle cell
/
cell damage
/
cell viability
/
controlled study
/
cytotoxicity
/
flow cytometry
/
gene targeting
/
hypoxia
/
in vitro study
/
mitochondrial membrane potential
/
mitochondrial permeability
/
nonhuman
/
oxidative stress
/
rat
/
reoxygenation
/
reperfusion injury
/
Western blotting
/
animal
/
cell hypoxia
/
cell line
/
cell survival
/
chemistry
/
cytology
/
drug effects
/
genetics
/
metabolism
/
mitochondrion
/
myocardial ischemia reperfusion injury
/
pathology
/
RNA interference
/
Cells
/
Nucleic Acids
/
Animals
/
Apoptosis
/
Calcium Channels
/
Cell Hypoxia
/
Cell Line
/
Cell Survival
/
Cyclosporine
/
Membrane Potential, Mitochondrial
/
Mitochondria
/
Myocardial Reperfusion Injury
/
Myocytes, Cardiac
/
Oxidative Stress
/
Rats
/
Reactive Oxygen Species
/
RNA Interference
/
RNA, Messenger
/
RNA, Small Interfering
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
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