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Title: The impact of LEP G-2548A and LEPR Gln223Arg polymorphisms on adiposity, leptin, and leptin-receptor serum levels in a Mexican Mestizo populationLanguage: InglésRepository: 34Subject: arginine / leptin / leptin receptor / leptin receptor, human / adult / Article / body fat / clinical article / controlled study / cross-sectional study / fat mass / female / genetic marker / genetic polymorphism / genotype / heterozygote / human / lipid metabolism / male / Mexican / obesity / population research / protein blood level / blood / body mass / genetic predisposition / genetics / Mexican American / Mexico / middle aged / pathology / single nucleotide polymorphism / Adiposity / Adult / Body Mass Index / Female / Genetic Predisposition to Disease / Genotype / Humans / Leptin / Lipid Metabolism / Male / Mexican Americans / Middle Aged / Obesity / Polymorphism, Single Nucleotide / Receptors, Leptin / 7 INGENIERÍA Y TECNOLOGÍA
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Title: The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob miceLanguage: InglésRepository: 34Subject: eprotirome / hormone receptor stimulating agent / liothyronine / sobetirome / thyroid hormone receptor / thyroid hormone receptor agonist / triacylglycerol / unclassified drug / 3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid / acetic acid derivative / anilide / glucose 6 phosphatase / glucose blood level / phenol derivative / animal experiment / animal model / animal tissue / Article / body temperature / controlled study / glucose tolerance / glycemic control / insulin resistance / insulin sensitivity / liver level / male / mouse / nonalcoholic fatty liver / nonhuman / ob/ob mouse / agonists / animal / biosynthesis / dose response / drug effects / enzyme induction / metabolism / mouse mutant / Non-alcoholic Fatty Liver Disease / time factor / Mus / Acetates / Anilides / Animals / Blood Glucose / Body Temperature / Dose-Response Relationship, Drug / Enzyme Induction / Glucose-6-Phosphatase / Insulin Resistance / Male / Mice / Mice, Obese / Phenols / Receptors, Thyroid Hormone / Time Factors / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Changes in T-tubules and sarcoplasmic reticulum in ventricular myocytes in early cardiac hypertrophy in a pressure overload rat modelLanguage: InglésRepository: 34Subject: calcium ion / aniline derivative / calcium / Fluo 4 / fluorescent dye / ion / xanthene derivative / animal cell / animal experiment / animal model / animal tissue / aorta constriction / Article / beta adrenergic stimulation / bone mass / calcium signaling / cell count / cell structure / cell volume / controlled study / decay time constant / density / diffusion / ex vivo study / heart left ventricle overload / heart muscle cell / heart muscle contractility / heart performance / heart ventricle hypertrophy / heart weight / male / nonhuman / priority journal / rat / sarcolemma / sarcoplasmic reticulum / tissue distribution / transverse tubular system / animal / cardiac muscle cell / cardiomegaly / cell culture / chemistry / confocal microscopy / cytology / disease model / fluorescence recovery after photobleaching / metabolism / microtubule / pathology / pressure / Wistar rat / Aniline Compounds / Animals / Calcium / Calcium Signaling / Cardiomegaly / Cells, Cultured / Disease Models, Animal / Fluorescence Recovery After Photobleaching / Fluorescent Dyes / Ions / Male / Microscopy, Confocal / Microtubules / Myocytes, Cardiac / Pressure / Rats / Rats, Wistar / Sarcoplasmic Reticulum / Xanthenes / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Multivariate Radiological-Based Models for the Prediction of Future Knee Pain: Data from the OAILanguage: InglésRepository: 34Subject: adult / Article / computer assisted diagnosis / computer prediction / controlled study / data analysis / diagnostic accuracy / elastic tissue / female / femur condyle / human / incidence / information processing / knee pain / male / middle aged / normal human / osteophyte / pain assessment / physician / quantitative analysis / quantitative study / radiography / aged / biological model / case control study / computer simulation / diagnostic imaging / factual database / image enhancement / knee / knee osteoarthritis / longitudinal study / multivariate analysis / pain / pain measurement / pathophysiology / statistical model / statistics and numerical data / Aged / Case-Control Studies / Computer Simulation / Databases, Factual / Female / Humans / Knee Joint / Linear Models / Longitudinal Studies / Male / Middle Aged / Models, Biological / Multivariate Analysis / Osteoarthritis, Knee / Pain / Pain Measurement / Radiographic Image Enhancement / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown FatLanguage: InglésRepository: 34Subject: eprotirome / hormone receptor stimulating agent / propranolol / sobetirome / thyroid hormone receptor / thyroid hormone receptor agonist / unclassified drug / adipocyte / animal cell / animal experiment / animal tissue / Article / brown adipose tissue / cold tolerance / controlled study / in vitro study / male / metabolic disorder / mouse / nonhuman / obesity / pharmacological procedures / priority journal / receptor blocking / subcutaneous fat / thermogenesis / white adipose tissue / animal / brown adipocyte / C57BL mouse / energy metabolism / metabolism / physiology / white adipocyte / Adipocytes, Brown / Adipocytes, White / Adipose Tissue, Brown / Adipose Tissue, White / Animals / Energy Metabolism / Mice / Mice, Inbred C57BL / Obesity / Receptors, Thyroid Hormone / Thermogenesis / 7 INGENIERÍA Y TECNOLOGÍA
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Title: The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors even Obesity in a Mexican-Mestizo PopulationLanguage: InglésRepository: 34Subject: adipocytokine / apolipoprotein A1 / apolipoprotein B / glucose / high density lipoprotein cholesterol / insulin / leptin / low density lipoprotein cholesterol / peroxisome proliferator activated receptor gamma 2 / peroxisome proliferator activated receptor gamma coactivator 1alpha / resistin / triacylglycerol / very low density lipoprotein cholesterol / genetic marker / peroxisome proliferator activated receptor gamma / PPARGC1A protein, human / transcription factor / abdominal obesity / adipogenesis / adult / allele / Article / body fat / body mass / controlled study / dyslipidemia / female / genetic polymorphism / genetic risk / glucose metabolism / hip circumference / human / major clinical study / male / Mestizo / Mexican / obesity / phenotype / polymerase chain reaction / restriction fragment length polymorphism / waist circumference / age distribution / aged / ethnology / genetic association study / genetic predisposition / genetics / incidence / Metabolic Diseases / Mexico / middle aged / risk factor / sex ratio / single nucleotide polymorphism / very elderly / young adult / Adult / Age Distribution / Aged / Aged, 80 and over / Alleles / Female / Genetic Association Studies / Genetic Markers / Genetic Predisposition to Disease / Humans / Incidence / Male / Middle Aged / Obesity / Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha / Polymorphism, Single Nucleotide / PPAR gamma / Risk Factors / Sex Distribution / Transcription Factors / Young Adult / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Topical anti-inflammatory effects of isorhamnetin glycosides isolated from opuntia ficus-indicaLanguage: InglésRepository: 34Subject: antiinflammatory agent / cyclooxygenase 2 / flavonoid glycoside / indometacin / interleukin 6 / isorhamnetin / isorhamnetin glucosyl pentoside / isorhamnetin glucosyl rhamnoside / isorhamnetin glucosyl rhamnosyl pentoside / isorhamnetin glucosyl rhamnosyl rhamnoside / isorhamnetin glycoside derivative / nitric oxide / Opuntia ficus indica extract / plant extract / tumor necrosis factor alpha / unclassified drug / 3-methylquercetin / cytokine / glycoside / quercetin / animal cell / animal experiment / animal model / antiinflammatory activity / Article / cell proliferation / cell viability / controlled study / cytokine production / drug identification / ear edema / enzyme activity / in vitro study / in vivo study / macrophage / male / medicinal plant / mouse / nonhuman / Opuntia ficus-indica / rat / analogs and derivatives / animal / chemistry / dose response / immunology / Opuntia / Otitis Externa / treatment outcome / Wistar rat / Animals / Anti-Inflammatory Agents / Cytokines / Dose-Response Relationship, Drug / Glycosides / Male / Plant Extracts / Quercetin / Rats / Rats, Wistar / Treatment Outcome / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Adiponectin levels in breast milk of overweight/obese and normal weight mothers in the metropolitan area of Monterrey, México [Niveles de adiponectina en leche materna de madres con sobrepeso/obesidad y con peso normal del área metropolitana de Monterrey, México]Language: EspañolRepository: 34Subject: adiponectin receptor / Article / breast feeding education / breast milk / correlation analysis / enzyme linked immunosorbent assay / female / human / infant / male / obesity / weight gain / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Improved Diagnostic Multimodal Biomarkers for Alzheimer's Disease and Mild Cognitive ImpairmentLanguage: InglésRepository: 34Subject: apolipoprotein D / biological marker / complement component C3 / monocyte chemotactic protein 4 / tau protein / aged / Alzheimer disease / angular gyrus / Article / calibration / case control study / cerebrospinal fluid analysis / classifier / clinical feature / controlled study / data base / data mining / diagnostic accuracy / diagnostic test accuracy study / diagnostic value / disease classification / erythrocyte count / female / genetic algorithm / hippocampus / human / lateral orbitofrontal cortex / major clinical study / male / medial orbitofrontal cortex / medical history / methodology / middle temporal gyrus / mild cognitive impairment / nuclear magnetic resonance imaging / positron emission tomography / protein blood level / sensitivity and specificity / superior frontal gyrus / temporal lobe / voxel based morphometry / cognitive defect / diagnostic imaging / early diagnosis / factual database / genetics / multimodal imaging / pathology / radiography / Alzheimer Disease / Biomarkers / Cognitive Dysfunction / Databases, Factual / Early Diagnosis / Humans / Magnetic Resonance Imaging / Multimodal Imaging / Radiography / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Enrichment of the cancer stem phenotype in sphere cultures of prostate cancer cell lines occurs through activation of developmental pathways mediated by the transcriptional regulator ΔNp63αLanguage: InglésRepository: 34Subject: Bcl2 related protein A1 / CD133 antigen / delta NP63alpha protein / early growth response factor 1 / regulator protein / unclassified drug / glycoprotein / leukocyte antigen / peptide / PROM1 protein, human / tumor marker / Article / BCL2A1 gene / bioassay / cancer stem cell / CD133+ cancer stem cell / cell growth / clonogenesis / controlled study / drug resistance / EGR1 gene / flow cytometry / GAS1 gene / gene expression profiling / human / human cell / IGFBP3 gene / in vitro study / in vivo study / male / phenotype / prostasphere assay / prostate cancer cell line / protein expression / protein function / transcription regulation / tumor invasion / upregulation / gene expression regulation / metabolism / pathology / prostate tumor / tumor cell line / AC133 Antigen / Antigens, CD / Biomarkers, Tumor / Cell Line, Tumor / Gene Expression Profiling / Gene Expression Regulation, Neoplastic / Glycoproteins / Humans / Male / Neoplastic Stem Cells / Peptides / Phenotype / Prostatic Neoplasms / 7 INGENIERÍA Y TECNOLOGÍA
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