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Title: A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray databaseLanguage: InglésRepository: 34Subject: 1 naphthyl isothiocyanate / acetylsalicylic acid / allopurinol / allyl alcohol / amiodarone / azathioprine / benzbromarone / bromobenzene / carbamazepine / carbon tetrachloride / chlorpromazine / cimetidine / clofibrate / coumarin / cyclophosphamide / cytochrome P450 family 1 / diazepam / diclofenac / doxepin / ethionine / fluphenazine / flutamide / gemfibrozil / glibenclamide / griseofulvin / haloperidol / hexachlorobenzene / indometacin / paracetamol / unindexed drug / cytotoxin / algorithm / Article / cluster analysis / data base / gene expression / genomics / human / liver cell / liver toxicity / machine learning / microarray analysis / nonhuman / skin absorption / toxic hepatitis / xenobiotic metabolism / animal / DNA microarray / dose response / drug effects / genetic database / genetics / liver / metabolism / mouse / preclinical study / procedures / time factor / toxicogenetics / unsupervised machine learning / Animals / Chemical and Drug Induced Liver Injury / Cytotoxins / Databases, Genetic / Dose-Response Relationship, Drug / Drug Evaluation, Preclinical / Genomics / Humans / Liver / Mice / Oligonucleotide Array Sequence Analysis / Time Factors / Toxicogenetics / Unsupervised Machine Learning / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenineLanguage: InglésRepository: 34Subject: ACTA2 protein / adenine / alpha smooth muscle actin / COL1A1 protein / collagen / connective tissue growth factor / creatinine / messenger RNA / transforming growth factor beta1 / unclassified drug / urea / adipose derived stem cell / animal experiment / animal model / animal tissue / Article / controlled study / creatinine blood level / creatinine urine level / human / human cell / kidney fibrosis / male / nonhuman / rat / stem cell transplantation / treatment outcome / urea blood level / adipose tissue / animal / cell culture / chemically induced / cytology / fibrosis / gene expression profiling / genetics / kidney disease / stem cell / Wistar rat / Adenine / Adipose Tissue / Animals / Cells, Cultured / Fibrosis / Gene Expression Profiling / Humans / Kidney Diseases / Male / Rats / Rats, Wistar / Stem Cells / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Enrichment of the cancer stem phenotype in sphere cultures of prostate cancer cell lines occurs through activation of developmental pathways mediated by the transcriptional regulator ΔNp63αLanguage: InglésRepository: 34Subject: Bcl2 related protein A1 / CD133 antigen / delta NP63alpha protein / early growth response factor 1 / regulator protein / unclassified drug / glycoprotein / leukocyte antigen / peptide / PROM1 protein, human / tumor marker / Article / BCL2A1 gene / bioassay / cancer stem cell / CD133+ cancer stem cell / cell growth / clonogenesis / controlled study / drug resistance / EGR1 gene / flow cytometry / GAS1 gene / gene expression profiling / human / human cell / IGFBP3 gene / in vitro study / in vivo study / male / phenotype / prostasphere assay / prostate cancer cell line / protein expression / protein function / transcription regulation / tumor invasion / upregulation / gene expression regulation / metabolism / pathology / prostate tumor / tumor cell line / AC133 Antigen / Antigens, CD / Biomarkers, Tumor / Cell Line, Tumor / Gene Expression Profiling / Gene Expression Regulation, Neoplastic / Glycoproteins / Humans / Male / Neoplastic Stem Cells / Peptides / Phenotype / Prostatic Neoplasms / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Bilateral Image Subtraction and Multivariate Models for the Automated Triaging of Screening MammogramsLanguage: InglésRepository: 34Subject: Article / automation / breast cancer / cancer risk / cancer screening / computer assisted diagnosis / controlled study / data base / diagnostic accuracy / diagnostic test accuracy study / digital imaging / human / image enhancement / image subtraction / major clinical study / mammography / methodology / probability / radiologist / sensitivity and specificity / tumor calcinosis / validation process / workflow / automated pattern recognition / breast tumor / computer simulation / diagnostic imaging / early cancer diagnosis / echography / emergency health service / female / middle aged / multivariate analysis / procedures / reproducibility / statistical model / Breast Neoplasms / Computer Simulation / Early Detection of Cancer / Female / Humans / Image Interpretation, Computer-Assisted / Mammography / Middle Aged / Models, Statistical / Multivariate Analysis / Pattern Recognition, Automated / Reproducibility of Results / Sensitivity and Specificity / Subtraction Technique / Triage / Ultrasonography
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Title: Influence of PEEK Coating on Hip Implant Stress Shielding: A Finite Element AnalysisLanguage: InglésRepository: 34Subject: polyetheretherketone / titanium / alloy / biocompatible coated material / hydroxyapatite / ketone / macrogol derivative / Article / body weight / bone regeneration / cortical bone / electrophoresis / finite element analysis / hip prosthesis / mechanical stress / osteolysis / stress shielding / surface property / tooth implant / trabecular bone / chemistry / devices / femur / hip replacement / human / osseointegration / pathology / pressure / procedures / prosthesis design / theoretical model / Alloys / Arthroplasty, Replacement, Hip / Coated Materials, Biocompatible / Durapatite / Femur / Finite Element Analysis / Hip Prosthesis / Humans / Ketones / Models, Theoretical / Osseointegration / Polyethylene Glycols / Pressure / Prosthesis Design / Stress, Mechanical / Titanium / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Relationship between irisin concentration and serum cytokines in mother and newbornLanguage: InglésRepository: 34Subject: cytokine / fatty acid / gamma interferon inducible protein 10 / interleukin 1 receptor blocking agent / interleukin 1beta / interleukin 5 / interleukin 7 / irisin / plasma protein / antioxidant / biological marker / CXCL10 protein, human / fibronectin / FNDC5 protein, human / interleukin derivative / adolescent / adult / arterial blood / Article / blood sampling / body weight / cesarean section / chemical parameters / clinical article / controlled study / cytokine blood level / female / gamma interferon inducible protein 10 blood level / hormone blood level / hormone determination / human / interleukin 1beta blood level / interleukin 5 blood level / interleukin 7 blood level / irisin blood level / labor / male / maternal blood / newborn / obesity / perinatal period / prediction / pregnancy diabetes mellitus / progeny / protein blood level / protein determination / total antioxidant capacity / umbilical cord blood / venous blood / blood / body mass / fetus blood / metabolism / mother / multivariate analysis / pregnancy / statistical model / young adult / Adolescent / Adult / Antioxidants / Biomarkers / Body Mass Index / Chemokine CXCL10 / Cytokines / Diabetes, Gestational / Fatty Acids / Female / Fetal Blood / Fibronectins / Humans / Infant, Newborn / Interleukins / Linear Models / Mothers / Multivariate Analysis / Pregnancy / Young Adult / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Association of Irisin Plasma Levels with Anthropometric Parameters in Children with Underweight, Normal Weight, Overweight, and ObesityLanguage: InglésRepository: 34Subject: albumin / glucose / irisin / low density lipoprotein cholesterol / triacylglycerol / fibronectin / FNDC5 protein, human / aerobic exercise / age / albumin blood level / anaerobic exercise / anthropometric parameters / Article / body composition / body mass / child / childhood obesity / cholesterol blood level / clinical article / controlled study / disease association / fat free mass / fat mass / female / glucose blood level / hormone blood level / human / male / metabolic parameters / muscle mass / physical activity / sex difference / underweight / waist circumference / blood / exercise / pathology / pathophysiology / preschool child / Body Mass Index / Child / Child, Preschool / Exercise / Female / Fibronectins / Humans / Male / Pediatric Obesity / Thinness / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Bilateral Image Subtraction and Multivariate Models for the Automated Triaging of Screening MammogramsLanguage: InglésRepository: 34Subject: Article / automation / breast cancer / cancer risk / cancer screening / computer assisted diagnosis / controlled study / data base / diagnostic accuracy / diagnostic test accuracy study / digital imaging / human / image enhancement / image subtraction / major clinical study / mammography / methodology / probability / radiologist / sensitivity and specificity / tumor calcinosis / validation process / workflow / automated pattern recognition / breast tumor / computer simulation / diagnostic imaging / early cancer diagnosis / echography / emergency health service / female / middle aged / multivariate analysis / procedures / reproducibility / statistical model / Breast Neoplasms / Computer Simulation / Early Detection of Cancer / Female / Humans / Image Interpretation, Computer-Assisted / Mammography / Middle Aged / Models, Statistical / Multivariate Analysis / Pattern Recognition, Automated / Reproducibility of Results / Sensitivity and Specificity / Subtraction Technique / Triage / Ultrasonography / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the BlindLanguage: InglésRepository: 34Subject: adult / aged / Article / camera / clinical article / clinical evaluation / conjunctival dehiscence / conjunctival erosion / controlled study / cornea opacity / device safety / endophthalmitis / Europe / female / follow up / function test / functional assessment / human / hypotony / keratitis / male / medical device complication / multicenter study / outcome assessment / personal experience / priority journal / prospective study / retina detachment / retina tear / retinal implant / United States / uveitis / vision / visual function test / blindness / clinical trial / electrode implant / microelectrode / middle aged / pathophysiology / physiology / prosthesis implantation / reproducibility / retinitis pigmentosa / single blind procedure / Vision, Low / visual acuity / visual prosthesis / Adult / Aged / Blindness / Electrodes, Implanted / Female / Follow-Up Studies / Humans / Male / Microelectrodes / Middle Aged / Prospective Studies / Prosthesis Implantation / Reproducibility of Results / Retinitis Pigmentosa / Single-Blind Method / Visual Acuity / Visual Prosthesis / 7 INGENIERÍA Y TECNOLOGÍA
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Title: Omental torsion. Case Report [Torsión de epiplón. Reporte de caso]Language: InglésRepository: 34Subject: abdominal pain / acute appendicitis / adult / Article / case report / computer assisted tomography / congenital malformation / disease predisposition / echography / human / laparoscopy / male / obesity / omental torsion / rectum abdominoperineal resection / stomach volvulus / young adult / acute abdomen / appendectomy / appendicitis / complication / diagnostic error / emergency / omentum / peritoneal disease / risk factor / torsion / Abdomen, Acute / Appendectomy / Appendicitis / Diagnostic Errors / Emergencies / Humans / Laparoscopy / Male / Omentum / Peritoneal Diseases / Risk Factors / Torsion Abnormality / Young Adult / 7 INGENIERÍA Y TECNOLOGÍA
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