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7 INGENIERÍA Y TECNOLOGÍA
(11)
Animals
(11)
animal
(11)
mouse
(11)
nonhuman
(11)
Article
(9)
Mice
(9)
animal experiment
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controlled study
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metabolism
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Subject:
animal tissue
Subject:
mouse
Language:
Inglés
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Title:
Cell source determines the immunological impact of biomimetic nanoparticles
Language:
Inglés
Repository:
34
Subject:
Antigen-antibody reactions
/
Biocompatibility
/
Biomimetics
/
Cell membranes
/
Drug delivery
/
Drug products
/
Immunology
/
Nanoparticles
/
Biomimetic nanoparticles
/
Biomimicry
/
Comprehensive evaluation
/
Immunobiology
/
Immunological effects
/
Nanovector
/
Systemic administration
/
Time-lapse microscopy
/
Biological materials
/
alanine aminotransferase
/
aspartate aminotransferase
/
biomimetic material
/
creatinine
/
gamma interferon
/
interleukin 10
/
interleukin 12
/
interleukin 1alpha
/
interleukin 1beta
/
interleukin 2
/
interleukin 3
/
interleukin 6
/
leukolike vector
/
multistage nanovector
/
nanocarrier
/
nanoparticle
/
reactive oxygen metabolite
/
transcription factor RelA
/
tumor necrosis factor alpha
/
unclassified drug
/
biomaterial
/
nanocapsule
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
biocompatibility
/
cell interaction
/
controlled study
/
cytokine release
/
drug delivery system
/
human
/
human cell
/
in vitro study
/
in vivo study
/
internalization
/
leukocyte membrane
/
liver function
/
macrophage
/
mononuclear phagocyte
/
mouse
/
nonhuman
/
opsonization
/
phagocytosis
/
priority journal
/
protein expression
/
static electricity
/
surface charge
/
time lapse imaging
/
zeta potential
/
animal
/
Bagg albino mouse
/
cell culture
/
comparative study
/
drug effects
/
evaluation study
/
immunology
/
innate immunity
/
leukocyte
/
Animals
/
Biocompatible Materials
/
Biomimetic Materials
/
Cells, Cultured
/
Immunity, Innate
/
Leukocytes
/
Mice
/
Mice, Inbred BALB C
/
Nanocapsules
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Genome-wide binding patterns of thyroid hormone receptor beta
Language:
Inglés
Repository:
34
Subject:
thyroid hormone receptor beta
/
transcription factor AP 1
/
transcription factor CTCF
/
ligand
/
protein binding
/
RNA
/
3' untranslated region
/
5' untranslated region
/
animal experiment
/
animal tissue
/
article
/
binding kinetics
/
binding site
/
controlled study
/
gene cluster
/
gene control
/
gene expression
/
gene repression
/
gene sequence
/
gene targeting
/
genetic association
/
genetic transcription
/
genetic transfection
/
human
/
human cell
/
liver cell
/
mouse
/
nonhuman
/
nucleotide sequence
/
protein analysis
/
protein function
/
protein localization
/
sequence analysis
/
animal
/
C57BL mouse
/
cell line
/
chemistry
/
DNA microarray
/
DNA responsive element
/
DNA sequence
/
gene expression regulation
/
genome
/
HepG2 cell line
/
liver
/
metabolism
/
multigene family
/
plasmid
/
Animals
/
Binding Sites
/
Cell Line
/
Gene Expression Regulation
/
Genome
/
Hep G2 Cells
/
Humans
/
Ligands
/
Liver
/
Mice
/
Mice, Inbred C57BL
/
Multigene Family
/
Oligonucleotide Array Sequence Analysis
/
Plasmids
/
Protein Binding
/
Response Elements
/
Sequence Analysis, DNA
/
Thyroid Hormone Receptors beta
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulence
Language:
Inglés
Repository:
34
Subject:
amino acid
/
arginine
/
bacterial protein
/
histidine
/
protein Mga
/
transcriptome
/
unclassified drug
/
virulence factor
/
mry protein, Streptococcus pyogenes
/
amino acid substitution
/
animal experiment
/
animal model
/
Article
/
bacterial gene
/
bacterial genome
/
bacterial strain
/
bacterial virulence
/
bacterium culture
/
codon
/
controlled study
/
gene expression
/
gene sequence
/
human
/
human cell
/
infectious arthritis
/
Macaca fascicularis
/
mga gene
/
mouse
/
nonhuman
/
nuclear magnetic resonance imaging
/
phenotype
/
priority journal
/
regulator gene
/
single nucleotide polymorphism
/
skin infection
/
soft tissue infection
/
Streptococcus group A
/
animal
/
arthropathy
/
cell line
/
female
/
genetics
/
hairless mouse
/
metabolism
/
microbiology
/
missense mutation
/
pathogenicity
/
pathology
/
Streptococcus infection
/
Streptococcus pyogenes
/
Amino Acid Substitution
/
Animals
/
Bacterial Proteins
/
Cell Line
/
Female
/
Genome, Bacterial
/
Humans
/
Joint Diseases
/
Mice
/
Mice, Hairless
/
Mutation, Missense
/
Polymorphism, Single Nucleotide
/
Streptococcal Infections
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
liothyronine
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
triacylglycerol
/
unclassified drug
/
3-((3,5-dibromo-4-(4-hydroxy-3-(1-methylethyl)phenoxy)phenyl)amino)-3-oxopropanoic acid
/
acetic acid derivative
/
anilide
/
glucose 6 phosphatase
/
glucose blood level
/
phenol derivative
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
body temperature
/
controlled study
/
glucose tolerance
/
glycemic control
/
insulin resistance
/
insulin sensitivity
/
liver level
/
male
/
mouse
/
nonalcoholic fatty liver
/
nonhuman
/
ob/ob mouse
/
agonists
/
animal
/
biosynthesis
/
dose response
/
drug effects
/
enzyme induction
/
metabolism
/
mouse mutant
/
Non-alcoholic Fatty Liver Disease
/
time factor
/
Mus
/
Acetates
/
Anilides
/
Animals
/
Blood Glucose
/
Body Temperature
/
Dose-Response Relationship, Drug
/
Enzyme Induction
/
Glucose-6-Phosphatase
/
Insulin Resistance
/
Male
/
Mice
/
Mice, Obese
/
Phenols
/
Receptors, Thyroid Hormone
/
Time Factors
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway
Language:
Inglés
Repository:
34
Subject:
mammalian target of rapamycin
/
nanoparticle
/
paclitaxel
/
phosphatidylinositol 3 kinase
/
protein kinase B
/
rapamycin
/
target of rapamycin kinase
/
animal experiment
/
animal model
/
animal tissue
/
antineoplastic activity
/
breast cancer
/
cancer inhibition
/
conference paper
/
controlled study
/
drug delivery system
/
drug potentiation
/
drug tumor level
/
female
/
in vitro study
/
liver
/
mouse
/
nanoencapsulation
/
nanopharmaceutics
/
nonhuman
/
particle size
/
protein phosphorylation
/
protein targeting
/
spleen
/
animal
/
apoptosis
/
cell proliferation
/
drug effects
/
human
/
Mammary Neoplasms, Animal
/
MCF 7 cell line
/
metabolism
/
nude mouse
/
signal transduction
/
tumor cell line
/
Animalia
/
Mus
/
Animals
/
Apoptosis
/
Cell Line, Tumor
/
Cell Proliferation
/
Female
/
Humans
/
MCF-7 Cells
/
Mice
/
Mice, Nude
/
Paclitaxel
/
Phosphatidylinositol 3-Kinases
/
Proto-Oncogene Proteins c-akt
/
Signal Transduction
/
Sirolimus
/
TOR Serine-Threonine Kinases
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat
Language:
Inglés
Repository:
34
Subject:
eprotirome
/
hormone receptor stimulating agent
/
propranolol
/
sobetirome
/
thyroid hormone receptor
/
thyroid hormone receptor agonist
/
unclassified drug
/
adipocyte
/
animal cell
/
animal experiment
/
animal tissue
/
Article
/
brown adipose tissue
/
cold tolerance
/
controlled study
/
in vitro study
/
male
/
metabolic disorder
/
mouse
/
nonhuman
/
obesity
/
pharmacological procedures
/
priority journal
/
receptor blocking
/
subcutaneous fat
/
thermogenesis
/
white adipose tissue
/
animal
/
brown adipocyte
/
C57BL mouse
/
energy metabolism
/
metabolism
/
physiology
/
white adipocyte
/
Adipocytes, Brown
/
Adipocytes, White
/
Adipose Tissue, Brown
/
Adipose Tissue, White
/
Animals
/
Energy Metabolism
/
Mice
/
Mice, Inbred C57BL
/
Obesity
/
Receptors, Thyroid Hormone
/
Thermogenesis
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Topical anti-inflammatory effects of isorhamnetin glycosides isolated from opuntia ficus-indica
Language:
Inglés
Repository:
34
Subject:
antiinflammatory agent
/
cyclooxygenase 2
/
flavonoid glycoside
/
indometacin
/
interleukin 6
/
isorhamnetin
/
isorhamnetin glucosyl pentoside
/
isorhamnetin glucosyl rhamnoside
/
isorhamnetin glucosyl rhamnosyl pentoside
/
isorhamnetin glucosyl rhamnosyl rhamnoside
/
isorhamnetin glycoside derivative
/
nitric oxide
/
Opuntia ficus indica extract
/
plant extract
/
tumor necrosis factor alpha
/
unclassified drug
/
3-methylquercetin
/
cytokine
/
glycoside
/
quercetin
/
animal cell
/
animal experiment
/
animal model
/
antiinflammatory activity
/
Article
/
cell proliferation
/
cell viability
/
controlled study
/
cytokine production
/
drug identification
/
ear edema
/
enzyme activity
/
in vitro study
/
in vivo study
/
macrophage
/
male
/
medicinal plant
/
mouse
/
nonhuman
/
Opuntia ficus-indica
/
rat
/
analogs and derivatives
/
animal
/
chemistry
/
dose response
/
immunology
/
Opuntia
/
Otitis Externa
/
treatment outcome
/
Wistar rat
/
Animals
/
Anti-Inflammatory Agents
/
Cytokines
/
Dose-Response Relationship, Drug
/
Glycosides
/
Male
/
Plant Extracts
/
Quercetin
/
Rats
/
Rats, Wistar
/
Treatment Outcome
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Supercritical CO2 foaming of thermoplastic materials derived from maize: Proof-of- concept use in mammalian cell culture applications
Language:
Inglés
Repository:
34
Subject:
carbon dioxide
/
formamide
/
glycerol
/
macrogol
/
plastic
/
plasticizer
/
sorbitol
/
starch
/
thermoplastic
/
unclassified drug
/
urea
/
vegetable protein
/
zein
/
biomaterial
/
22RV1 cell line
/
3T3 cell line
/
animal cell
/
Article
/
assay
/
cell adhesion
/
cell culture
/
cell proliferation
/
DU145 cell line
/
fibroblast
/
flour
/
foam
/
foaming
/
maize
/
mammal cell
/
mouse
/
nonhuman
/
plant seed
/
porosity
/
prostate cancer cell line
/
supercritical carbon dioxide foaming
/
animal
/
cell culture technique
/
cell line
/
human
/
materials testing
/
temperature
/
Mammalia
/
Zea mays
/
Animals
/
Biocompatible Materials
/
Carbon Dioxide
/
Cell Culture Techniques
/
Cell Line
/
Humans
/
Materials Testing
/
Mice
/
Porosity
/
Temperature
/
Zein
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database
Language:
Inglés
Repository:
34
Subject:
1 naphthyl isothiocyanate
/
acetylsalicylic acid
/
allopurinol
/
allyl alcohol
/
amiodarone
/
azathioprine
/
benzbromarone
/
bromobenzene
/
carbamazepine
/
carbon tetrachloride
/
chlorpromazine
/
cimetidine
/
clofibrate
/
coumarin
/
cyclophosphamide
/
cytochrome P450 family 1
/
diazepam
/
diclofenac
/
doxepin
/
ethionine
/
fluphenazine
/
flutamide
/
gemfibrozil
/
glibenclamide
/
griseofulvin
/
haloperidol
/
hexachlorobenzene
/
indometacin
/
paracetamol
/
unindexed drug
/
cytotoxin
/
algorithm
/
Article
/
cluster analysis
/
data base
/
gene expression
/
genomics
/
human
/
liver cell
/
liver toxicity
/
machine learning
/
microarray analysis
/
nonhuman
/
skin absorption
/
toxic hepatitis
/
xenobiotic metabolism
/
animal
/
DNA microarray
/
dose response
/
drug effects
/
genetic database
/
genetics
/
liver
/
metabolism
/
mouse
/
preclinical study
/
procedures
/
time factor
/
toxicogenetics
/
unsupervised machine learning
/
Animals
/
Chemical and Drug Induced Liver Injury
/
Cytotoxins
/
Databases, Genetic
/
Dose-Response Relationship, Drug
/
Drug Evaluation, Preclinical
/
Genomics
/
Humans
/
Liver
/
Mice
/
Oligonucleotide Array Sequence Analysis
/
Time Factors
/
Toxicogenetics
/
Unsupervised Machine Learning
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture
Language:
Inglés
Repository:
34
Subject:
acute phase protein
/
autacoid
/
lipid
/
messenger RNA
/
scleroprotein
/
somatomedin C
/
cadherin
/
cytoskeleton protein
/
insulin-like growth factor-1, mouse
/
somatomedin receptor
/
tight junction protein
/
acute phase response
/
animal experiment
/
animal tissue
/
Article
/
cell junction
/
cell polarity
/
controlled study
/
cytoskeleton
/
extracellular matrix
/
gene expression regulation
/
gene overexpression
/
heterozygosity
/
histology
/
igf1 gene
/
inflammation
/
lipid peroxidation
/
liver structure
/
liver tissue
/
male
/
microarray analysis
/
mouse
/
murine model
/
nonhuman
/
oxidative stress
/
protein analysis
/
protein blood level
/
protein deficiency
/
protein function
/
reverse transcription polymerase chain reaction
/
wild type
/
animal
/
comparative study
/
cross breeding
/
desmosome
/
gene expression profiling
/
genetics
/
hepatitis
/
immunology
/
liver
/
metabolism
/
pathology
/
subcutaneous drug administration
/
transgenic mouse
/
Acute-Phase Proteins
/
Animals
/
Cadherins
/
Crosses, Genetic
/
Cytoskeletal Proteins
/
Desmosomes
/
Extracellular Matrix Proteins
/
Gene Expression Profiling
/
Gene Expression Regulation
/
Hepatitis
/
Inflammation Mediators
/
Injections, Subcutaneous
/
Insulin-Like Growth Factor I
/
Lipid Peroxidation
/
Liver
/
Male
/
Mice
/
Mice, Transgenic
/
Oxidative Stress
/
Receptors, Somatomedin
/
Tight Junction Proteins
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
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