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7 INGENIERÍA Y TECNOLOGÍA
(7)
Animals
(7)
animal
(7)
genetics
(7)
nonhuman
(7)
Article
(6)
animal experiment
(6)
controlled study
(6)
metabolism
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Subject:
animal
Subject:
genetics
Subject:
nonhuman
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Title:
A naturally occurring single amino acid replacement in multiple gene regulator of group a streptococcus significantly increases virulence
Language:
Inglés
Repository:
34
Subject:
amino acid
/
arginine
/
bacterial protein
/
histidine
/
protein Mga
/
transcriptome
/
unclassified drug
/
virulence factor
/
mry protein, Streptococcus pyogenes
/
amino acid substitution
/
animal experiment
/
animal model
/
Article
/
bacterial gene
/
bacterial genome
/
bacterial strain
/
bacterial virulence
/
bacterium culture
/
codon
/
controlled study
/
gene expression
/
gene sequence
/
human
/
human cell
/
infectious arthritis
/
Macaca fascicularis
/
mga gene
/
mouse
/
nonhuman
/
nuclear magnetic resonance imaging
/
phenotype
/
priority journal
/
regulator gene
/
single nucleotide polymorphism
/
skin infection
/
soft tissue infection
/
Streptococcus group A
/
animal
/
arthropathy
/
cell line
/
female
/
genetics
/
hairless mouse
/
metabolism
/
microbiology
/
missense mutation
/
pathogenicity
/
pathology
/
Streptococcus infection
/
Streptococcus pyogenes
/
Amino Acid Substitution
/
Animals
/
Bacterial Proteins
/
Cell Line
/
Female
/
Genome, Bacterial
/
Humans
/
Joint Diseases
/
Mice
/
Mice, Hairless
/
Mutation, Missense
/
Polymorphism, Single Nucleotide
/
Streptococcal Infections
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Small Interfering RNA Targeting Mitochondrial Calcium Uniporter Improves Cardiomyocyte Cell Viability in Hypoxia/Reoxygenation Injury by Reducing Calcium Overload
Language:
Inglés
Repository:
34
Subject:
Cell death
/
Microcontrollers
/
Calcium overload
/
Cell viability
/
Cellular injury
/
Intracellular Ca
/
Mitochondrial calcium uniporter
/
Mitochondrial dysfunction
/
Small interfering RNA
/
Therapeutic strategy
/
Calcium
/
calcium
/
small interfering RNA
/
calcium channel
/
cyclosporin
/
messenger RNA
/
mitochondrial calcium uniporter
/
reactive oxygen metabolite
/
animal cell
/
animal experiment
/
apoptosis
/
Article
/
cardiac muscle cell
/
cell damage
/
cell viability
/
controlled study
/
cytotoxicity
/
flow cytometry
/
gene targeting
/
hypoxia
/
in vitro study
/
mitochondrial membrane potential
/
mitochondrial permeability
/
nonhuman
/
oxidative stress
/
rat
/
reoxygenation
/
reperfusion injury
/
Western blotting
/
animal
/
cell hypoxia
/
cell line
/
cell survival
/
chemistry
/
cytology
/
drug effects
/
genetics
/
metabolism
/
mitochondrion
/
myocardial ischemia reperfusion injury
/
pathology
/
RNA interference
/
Cells
/
Nucleic Acids
/
Animals
/
Apoptosis
/
Calcium Channels
/
Cell Hypoxia
/
Cell Line
/
Cell Survival
/
Cyclosporine
/
Membrane Potential, Mitochondrial
/
Mitochondria
/
Myocardial Reperfusion Injury
/
Myocytes, Cardiac
/
Oxidative Stress
/
Rats
/
Reactive Oxygen Species
/
RNA Interference
/
RNA, Messenger
/
RNA, Small Interfering
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
An Influenza A/H1N1/2009 hemagglutinin vaccine produced in Escherichia coli
Language:
Inglés
Repository:
34
Subject:
hemagglutinin 63-286
/
influenza vaccine
/
Influenza virus hemagglutinin
/
neutralizing antibody
/
recombinant protein
/
unclassified drug
/
virus antibody
/
virus hemagglutinin
/
animal cell
/
animal experiment
/
animal model
/
antibody production
/
antigen binding
/
article
/
bioassay
/
cell lysate
/
controlled study
/
dose response
/
drug binding
/
drug dose comparison
/
drug purification
/
Escherichia coli
/
ferret
/
human
/
immunogenicity
/
influenza A (H1N1)
/
Influenza virus A H1N1
/
molecular recognition
/
nonhuman
/
nucleotide sequence
/
protein expression
/
protein folding
/
protein purification
/
single drug dose
/
ultracentrifugation
/
vaccine production
/
animal
/
blood
/
chemistry
/
enzyme linked immunosorbent assay
/
genetics
/
immunology
/
metabolism
/
reverse transcription polymerase chain reaction
/
Adolescent
/
Adult
/
Aged
/
Aged, 80 and over
/
Antibodies, Viral
/
Australia
/
Child
/
Child, Preschool
/
Cohort Studies
/
Humans
/
Influenza A Virus, H1N1 Subtype
/
Influenza, Human
/
Male
/
Middle Aged
/
Pandemics
/
Seasons
/
Young Adult
/
Animals
/
Enzyme-Linked Immunosorbent Assay
/
Ferrets
/
Hemagglutinins, Viral
/
Influenza Vaccines
/
Protein Folding
/
Reverse Transcriptase Polymerase Chain Reaction
/
Bacteria (microorganisms)
/
Hexapoda
/
Mammalia
/
Mustela
/
Prokaryota
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database
Language:
Inglés
Repository:
34
Subject:
1 naphthyl isothiocyanate
/
acetylsalicylic acid
/
allopurinol
/
allyl alcohol
/
amiodarone
/
azathioprine
/
benzbromarone
/
bromobenzene
/
carbamazepine
/
carbon tetrachloride
/
chlorpromazine
/
cimetidine
/
clofibrate
/
coumarin
/
cyclophosphamide
/
cytochrome P450 family 1
/
diazepam
/
diclofenac
/
doxepin
/
ethionine
/
fluphenazine
/
flutamide
/
gemfibrozil
/
glibenclamide
/
griseofulvin
/
haloperidol
/
hexachlorobenzene
/
indometacin
/
paracetamol
/
unindexed drug
/
cytotoxin
/
algorithm
/
Article
/
cluster analysis
/
data base
/
gene expression
/
genomics
/
human
/
liver cell
/
liver toxicity
/
machine learning
/
microarray analysis
/
nonhuman
/
skin absorption
/
toxic hepatitis
/
xenobiotic metabolism
/
animal
/
DNA microarray
/
dose response
/
drug effects
/
genetic database
/
genetics
/
liver
/
metabolism
/
mouse
/
preclinical study
/
procedures
/
time factor
/
toxicogenetics
/
unsupervised machine learning
/
Animals
/
Chemical and Drug Induced Liver Injury
/
Cytotoxins
/
Databases, Genetic
/
Dose-Response Relationship, Drug
/
Drug Evaluation, Preclinical
/
Genomics
/
Humans
/
Liver
/
Mice
/
Oligonucleotide Array Sequence Analysis
/
Time Factors
/
Toxicogenetics
/
Unsupervised Machine Learning
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine
Language:
Inglés
Repository:
34
Subject:
ACTA2 protein
/
adenine
/
alpha smooth muscle actin
/
COL1A1 protein
/
collagen
/
connective tissue growth factor
/
creatinine
/
messenger RNA
/
transforming growth factor beta1
/
unclassified drug
/
urea
/
adipose derived stem cell
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
controlled study
/
creatinine blood level
/
creatinine urine level
/
human
/
human cell
/
kidney fibrosis
/
male
/
nonhuman
/
rat
/
stem cell transplantation
/
treatment outcome
/
urea blood level
/
adipose tissue
/
animal
/
cell culture
/
chemically induced
/
cytology
/
fibrosis
/
gene expression profiling
/
genetics
/
kidney disease
/
stem cell
/
Wistar rat
/
Adenine
/
Adipose Tissue
/
Animals
/
Cells, Cultured
/
Fibrosis
/
Gene Expression Profiling
/
Humans
/
Kidney Diseases
/
Male
/
Rats
/
Rats, Wistar
/
Stem Cells
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
IGF-1 modulates gene expression of proteins involved in inflammation, cytoskeleton, and liver architecture
Language:
Inglés
Repository:
34
Subject:
acute phase protein
/
autacoid
/
lipid
/
messenger RNA
/
scleroprotein
/
somatomedin C
/
cadherin
/
cytoskeleton protein
/
insulin-like growth factor-1, mouse
/
somatomedin receptor
/
tight junction protein
/
acute phase response
/
animal experiment
/
animal tissue
/
Article
/
cell junction
/
cell polarity
/
controlled study
/
cytoskeleton
/
extracellular matrix
/
gene expression regulation
/
gene overexpression
/
heterozygosity
/
histology
/
igf1 gene
/
inflammation
/
lipid peroxidation
/
liver structure
/
liver tissue
/
male
/
microarray analysis
/
mouse
/
murine model
/
nonhuman
/
oxidative stress
/
protein analysis
/
protein blood level
/
protein deficiency
/
protein function
/
reverse transcription polymerase chain reaction
/
wild type
/
animal
/
comparative study
/
cross breeding
/
desmosome
/
gene expression profiling
/
genetics
/
hepatitis
/
immunology
/
liver
/
metabolism
/
pathology
/
subcutaneous drug administration
/
transgenic mouse
/
Acute-Phase Proteins
/
Animals
/
Cadherins
/
Crosses, Genetic
/
Cytoskeletal Proteins
/
Desmosomes
/
Extracellular Matrix Proteins
/
Gene Expression Profiling
/
Gene Expression Regulation
/
Hepatitis
/
Inflammation Mediators
/
Injections, Subcutaneous
/
Insulin-Like Growth Factor I
/
Lipid Peroxidation
/
Liver
/
Male
/
Mice
/
Mice, Transgenic
/
Oxidative Stress
/
Receptors, Somatomedin
/
Tight Junction Proteins
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
Title:
Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins
Language:
Inglés
Repository:
34
Subject:
angiotensin II
/
calcium
/
connective tissue growth factor
/
contractile protein
/
protein Grem1
/
scleroprotein
/
somatomedin B
/
somatomedin B receptor
/
somatomedin binding protein 1
/
somatomedin binding protein 2
/
somatomedin binding protein 3
/
somatomedin binding protein 4
/
somatomedin binding protein 5
/
somatomedin binding protein 6
/
somatomedin C
/
somatomedin C receptor
/
unclassified drug
/
bradykinin
/
animal experiment
/
animal model
/
animal tissue
/
Article
/
calcium homeostasis
/
controlled study
/
coronary artery blood flow
/
Ctgf gene
/
extracellular matrix
/
gene
/
gene expression
/
Grem1 gene
/
heart muscle contractility
/
heart muscle fibrosis
/
heart weight
/
histology
/
Igf1 gene
/
Igf1r gene
/
Igf2 gene
/
Igf2r gene
/
Igfbp1 gene
/
Igfbp2 gene
/
Igfbp3 gene
/
Igfbp4 gene
/
Igfbp5 gene
/
Igfbp6 gene
/
male
/
mouse
/
nonhuman
/
protein blood level
/
real time polymerase chain reaction
/
regulatory mechanism
/
reperfusion injury
/
animal
/
body weight
/
cardiac muscle
/
deficiency
/
drug effects
/
gene expression regulation
/
genetics
/
heart contraction
/
hemodynamics
/
metabolism
/
organ size
/
pathology
/
perfusion
/
transgenic mouse
/
vasoconstriction
/
vasodilatation
/
Angiotensin II
/
Animals
/
Body Weight
/
Bradykinin
/
Extracellular Matrix
/
Gene Expression Regulation
/
Hemodynamics
/
Insulin-Like Growth Factor I
/
Mice, Transgenic
/
Myocardial Contraction
/
Myocardium
/
Organ Size
/
Perfusion
/
Real-Time Polymerase Chain Reaction
/
Vasoconstriction
/
Vasodilation
/
7 INGENIERÍA Y TECNOLOGÍA
Acceder
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